Toxicity WHO grade 3/4
| . | BACOPP . | HD9elderly . | |||
|---|---|---|---|---|---|
| WHO grade, no. of patients . | WHO grade 3/4, % . | WHO grade 3/4, % . | |||
| III . | IV . | COPP/ABVD . | BEACOPP baseline . | ||
| Anemia | 9 | 1 | 17 | 24 | 41 |
| Thrombopenia | 2 | 11 | 22 | 16 | 49 |
| Leucopenia | 10 | 32 | 70 | 84 | 92 |
| Infection | 12 | 2 | 23 | 12 | 23 |
| Nausea | 5 | 8 | 12 | 18 | |
| Mucositis | 7 | 12 | 13 | ||
| Gastrointestinal tract | 3 | 5 | 4 | 3 | |
| Respiratory | 4 | 3 | 12 | 8 | |
| Cardiac | 4 | 1 | 8 | 8 | 15 |
| Neurotoxicity | 6 | 1 | 12 | 12 | 13 |
| . | BACOPP . | HD9elderly . | |||
|---|---|---|---|---|---|
| WHO grade, no. of patients . | WHO grade 3/4, % . | WHO grade 3/4, % . | |||
| III . | IV . | COPP/ABVD . | BEACOPP baseline . | ||
| Anemia | 9 | 1 | 17 | 24 | 41 |
| Thrombopenia | 2 | 11 | 22 | 16 | 49 |
| Leucopenia | 10 | 32 | 70 | 84 | 92 |
| Infection | 12 | 2 | 23 | 12 | 23 |
| Nausea | 5 | 8 | 12 | 18 | |
| Mucositis | 7 | 12 | 13 | ||
| Gastrointestinal tract | 3 | 5 | 4 | 3 | |
| Respiratory | 4 | 3 | 12 | 8 | |
| Cardiac | 4 | 1 | 8 | 8 | 15 |
| Neurotoxicity | 6 | 1 | 12 | 12 | 13 |
WHO indicates World Health Organization; BACOPP, bleomycin, Adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone; HD9elderly, German Hodgkin Study Group trial; COPP/ABVD, cyclophosphamide, vincristine (Oncovin), procarbazine, and prednisone/adriamycin, bleomycin, vincristine, and dacarbazine; and BEACOPP, bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine (Oncovin), procarbazine, and prednisone.