Prevalence and type of antibodies in secondary AIHA in adults
| Underlying disease or condition . | Prevalence of AIHA, %* . | WAIHA . | CAIHA . | References . |
|---|---|---|---|---|
| CLL | 2.3-4.3 | 87% | 7% | 16,17 |
| NHL (except CLL) | 2.6 | More common | Less common | 18 |
| IgM gammopathy | 1.1 | No | All | 19 |
| Hodgkin lymphoma | 0.19-1.7 | Almost all | Rare | 20 |
| Solid tumors | Very rare | 2/3 | 1/3 | 21 |
| Ovarian dermoid cyst | Very rare | All | No | 22 |
| SLE | 6.1 | Almost all | Rare | 23 |
| Ulcerative colitis | 1.7 | All | No | 24 |
| CVID | 5.5 | All | No | 25 |
| ALPD | 50 | All | No | 26 |
| After allogeneic SCT | 4.4 | Yes | Yes | 27 |
| After organ transplantation | 5.6 (pancreas) | Yes | No | 28 |
| Drug-induced in CLL | 2.9-10.5 | Almost all | Rare | 29 |
| Interferon α | Incidence: 11.5/100 000 patient-years | All | 0 | 30 |
| Underlying disease or condition . | Prevalence of AIHA, %* . | WAIHA . | CAIHA . | References . |
|---|---|---|---|---|
| CLL | 2.3-4.3 | 87% | 7% | 16,17 |
| NHL (except CLL) | 2.6 | More common | Less common | 18 |
| IgM gammopathy | 1.1 | No | All | 19 |
| Hodgkin lymphoma | 0.19-1.7 | Almost all | Rare | 20 |
| Solid tumors | Very rare | 2/3 | 1/3 | 21 |
| Ovarian dermoid cyst | Very rare | All | No | 22 |
| SLE | 6.1 | Almost all | Rare | 23 |
| Ulcerative colitis | 1.7 | All | No | 24 |
| CVID | 5.5 | All | No | 25 |
| ALPD | 50 | All | No | 26 |
| After allogeneic SCT | 4.4 | Yes | Yes | 27 |
| After organ transplantation | 5.6 (pancreas) | Yes | No | 28 |
| Drug-induced in CLL | 2.9-10.5 | Almost all | Rare | 29 |
| Interferon α | Incidence: 11.5/100 000 patient-years | All | 0 | 30 |
NHL indicates non-Hodgkin lymphoma; SLE, systemic lupus erythematosus; CVID, common variable immune deficiency; ALPD, autoimmune lymphoproliferative disease; and SCT, stem cell transplantation.
Data from recent and/or larger studies.