Table 1 Common integration sites in... | American Society of Hematology

Table 1

Common integration sites in CALM-AF10 mice infected with the MOL4070LTR retrovirus

Gene	Incidence	Occurrence in RTCGD*	Mouse ID
Nf1	12†	30	13, 17, 23, 25, 26, 31, 36, 40, 42, 44, 96, 98
Zeb2	11†	14	5, 17, 21, 23, 25, 26, 27, 36, 51, 80, 98
Mn1	6	12	25, 38, 39, 46, 67, 80
Evi1	5	19	6, 14, 29, 31, 36
Mllt3	3	2‡	14, 47, 69
Plag1	2	8	21, 42
Mpl	2	0‡	10, 80
Prkcz	2	0‡	17, 31
CX763467	2	0‡	25, 42
Foxp1	2	1‡	35, 88
Kras	2	8	20, 27
Rras2	2	35	39, 98
Tle3	2	4‡	40, 69
Phb	2	1‡	69, 96
Ift57/Cd47	2	2‡	36, 69
Erg	2	6	6, 69
Vav1	2	0‡	15, 74
Gata1	2	0‡	14, 47
Cybb	2	0‡	40, 8

Gene	Incidence	Occurrence in RTCGD*	Mouse ID
Nf1	12†	30	13, 17, 23, 25, 26, 31, 36, 40, 42, 44, 96, 98
Zeb2	11†	14	5, 17, 21, 23, 25, 26, 27, 36, 51, 80, 98
Mn1	6	12	25, 38, 39, 46, 67, 80
Evi1	5	19	6, 14, 29, 31, 36
Mllt3	3	2‡	14, 47, 69
Plag1	2	8	21, 42
Mpl	2	0‡	10, 80
Prkcz	2	0‡	17, 31
CX763467	2	0‡	25, 42
Foxp1	2	1‡	35, 88
Kras	2	8	20, 27
Rras2	2	35	39, 98
Tle3	2	4‡	40, 69
Phb	2	1‡	69, 96
Ift57/Cd47	2	2‡	36, 69
Erg	2	6	6, 69
Vav1	2	0‡	15, 74
Gata1	2	0‡	14, 47
Cybb	2	0‡	40, 8

Data from retroviral insertion studies in hematologic malignancies include 2783 total insertions.

Includes integrations identified by Southern blot analysis.

Not previously identified as a common integration site.