Table 1

Suggested template evaluation to verify lack of IgG antibody

Serum IgG < 150 mg/dLRepeat serum immune globulins for verification; no antibody testing required
Serum IgG between 150 and 250 mg/dL Repeat serum immune globulins for verification; Consider testing antibodies to tetanus and diphtheria or other protein based vaccines; optional, non conjugated pneumococcal vaccine and test 4 weeks after vaccination. 
Serum IgG between 250 and 450 mg/dL Repeat serum immune globulins for verification. Test antibodies to tetanus and diphtheria or other protein-based vaccines; also nonconjugated pneumococcal vaccine and test 4 weeks after vaccination. 
Serum IgG between 450 and 600 mg/dL Repeat serum immune globulins for verification. Test antibodies to tetanus and diphtheria and also other protein-based vaccines (measles mumps rubella, H zoster) also nonconjugated pneumococcal vaccine and test 4 weeks after vaccination 
Serum IgG < 150 mg/dLRepeat serum immune globulins for verification; no antibody testing required
Serum IgG between 150 and 250 mg/dL Repeat serum immune globulins for verification; Consider testing antibodies to tetanus and diphtheria or other protein based vaccines; optional, non conjugated pneumococcal vaccine and test 4 weeks after vaccination. 
Serum IgG between 250 and 450 mg/dL Repeat serum immune globulins for verification. Test antibodies to tetanus and diphtheria or other protein-based vaccines; also nonconjugated pneumococcal vaccine and test 4 weeks after vaccination. 
Serum IgG between 450 and 600 mg/dL Repeat serum immune globulins for verification. Test antibodies to tetanus and diphtheria and also other protein-based vaccines (measles mumps rubella, H zoster) also nonconjugated pneumococcal vaccine and test 4 weeks after vaccination 

IgG indicates immunoglobulin.

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