Total number of Mac-1+, F4/80+, and cytoplasmic IL-6+ cells in various organs
| Organ . | Mac1+, F4/80+, ×106 . | Mac1+,F4/80+, cytoplasmic IL-6+, ×103 . | ||
|---|---|---|---|---|
| WT . | SHIP−/− . | WT . | SHIP−/− . | |
| Spleen | 4.7 ± 2 | 14.6 ± 4 | 2700 ± 700 | 9500 ± 4200 |
| Bone marrow | 0.6 ± 0.2 | 0.5 ± 0.1 | 260 ± 45 | 100 ± 10 |
| Liver | 0.26 ± 0.2 | 0.33 ± 0.2 | 150 ± 50 | 200 ± 76 |
| Peritoneum | 1.3 ± 0.3 | 1.7 ± 1.2 | 106 ± 9 | 1200 ± 226 |
| Blood | 0.7 ± 0.5 | 2.3 ± 0.8 | 300 ± 18 | 210 ± 10 |
| Lung | 0.5 ± 0.2 | 3.4 ± 0.9 | 125 ± 7 | 450 ± 69 |
| Organ . | Mac1+, F4/80+, ×106 . | Mac1+,F4/80+, cytoplasmic IL-6+, ×103 . | ||
|---|---|---|---|---|
| WT . | SHIP−/− . | WT . | SHIP−/− . | |
| Spleen | 4.7 ± 2 | 14.6 ± 4 | 2700 ± 700 | 9500 ± 4200 |
| Bone marrow | 0.6 ± 0.2 | 0.5 ± 0.1 | 260 ± 45 | 100 ± 10 |
| Liver | 0.26 ± 0.2 | 0.33 ± 0.2 | 150 ± 50 | 200 ± 76 |
| Peritoneum | 1.3 ± 0.3 | 1.7 ± 1.2 | 106 ± 9 | 1200 ± 226 |
| Blood | 0.7 ± 0.5 | 2.3 ± 0.8 | 300 ± 18 | 210 ± 10 |
| Lung | 0.5 ± 0.2 | 3.4 ± 0.9 | 125 ± 7 | 450 ± 69 |
Values are from 3 or 4 animals of each strain at 7 to 8 weeks of age.
WT indicates wild-type; and SHIP, Src homology 2 domain-containing inositol 5-phosphatase.