Mean change in clot lysis time* with 1 SD increase in fibrinolytic factor
| . | Simple models† . | Multiple models‡ . | ||
|---|---|---|---|---|
| β (95%CI) . | R2 . | β (95% CI) . | R2 . | |
| Plasminogen | 0.04 (−0.03 to 0.12) | 0 | −0.10 (−0.158 to −0.045) | 0.53 |
| α2-antiplasmin | 0.26 (0.19-0.33) | 0.07 | 0.20 (0.14-0.25) | |
| TAFI | 0.40 (0.33-0.47) | 0.16 | 0.28 (0.23-0.34) | |
| PAI-1* | 0.63 (0.58-0.69) | 0.40 | 0.54 (0.48-0.59) | |
| t-PA* | 0.39 (0.32-0.45) | 0.15 | 0.08 (0.03-0.14) | |
| . | Simple models† . | Multiple models‡ . | ||
|---|---|---|---|---|
| β (95%CI) . | R2 . | β (95% CI) . | R2 . | |
| Plasminogen | 0.04 (−0.03 to 0.12) | 0 | −0.10 (−0.158 to −0.045) | 0.53 |
| α2-antiplasmin | 0.26 (0.19-0.33) | 0.07 | 0.20 (0.14-0.25) | |
| TAFI | 0.40 (0.33-0.47) | 0.16 | 0.28 (0.23-0.34) | |
| PAI-1* | 0.63 (0.58-0.69) | 0.40 | 0.54 (0.48-0.59) | |
| t-PA* | 0.39 (0.32-0.45) | 0.15 | 0.08 (0.03-0.14) | |
CI indicates confidence interval; PAI-1, plasminogen activator inhibitor 1; TAFI, thrombin-activatable fibrinolysis inhibitor; and t-PA, tissue plasminogen activator.
Clot lysis time, PAI-1, and t-PA were 10 log-transformed.
In each of 5 different models, model clot lysis time was the dependent variable, and only 1 of the fibrinolytic factors was the independent variable.
Clot lysis time was the dependent variable and all 5 fibrinolytic factors simultaneously were independent variables in the model.