Table 1

Genes involved in the “DNA damage” functional category, deregulated by Zalypsis in MM1S cells

Probe setGene symbolMM1S FCDescription
212986_s_at TLK2 −2.65 Tousled-like kinase 2 
203725_at GADD45A 2.58 Growth arrest and DNA-damage-inducible, alpha 
222879_s_at POLH 3.34 Polymerase (DNA directed), eta 
203409_at DDB2 3.81 Damage-specific DNA binding protein 2, 48kDa 
205072_s_at XRCC4 −9.32 X-ray repair complementing defective repair in cells 4 
208393_s_at RAD50 −3.93 RAD50 homolog (S cerevisiae
208643_s_at XRCC5 −2.50 X-ray repair complementing defective repair in cells 5 
235609_at BRIP1 −2.42 BRCA1-interacting protein C-terminal helicase 1 
239635_at TMEM137 2.52 RNA-binding motif protein 14 
205875_s_at TREX1 2.72 Three prime repair exonuclease 1 
238736_at REV3L 4.18 REV3-like, catalytic subunit of DNA polymerase zeta (yeast) 
Probe setGene symbolMM1S FCDescription
212986_s_at TLK2 −2.65 Tousled-like kinase 2 
203725_at GADD45A 2.58 Growth arrest and DNA-damage-inducible, alpha 
222879_s_at POLH 3.34 Polymerase (DNA directed), eta 
203409_at DDB2 3.81 Damage-specific DNA binding protein 2, 48kDa 
205072_s_at XRCC4 −9.32 X-ray repair complementing defective repair in cells 4 
208393_s_at RAD50 −3.93 RAD50 homolog (S cerevisiae
208643_s_at XRCC5 −2.50 X-ray repair complementing defective repair in cells 5 
235609_at BRIP1 −2.42 BRCA1-interacting protein C-terminal helicase 1 
239635_at TMEM137 2.52 RNA-binding motif protein 14 
205875_s_at TREX1 2.72 Three prime repair exonuclease 1 
238736_at REV3L 4.18 REV3-like, catalytic subunit of DNA polymerase zeta (yeast) 
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