Multivariate analyses of relapse
| Variable . | n . | RR (95% Confidence interval) . | P . |
|---|---|---|---|
| All patients* | |||
| 0-MM | 56 | 0.7 (0.4-1.3) | .211 |
| 1-MM | 352 | Reference | |
| 2-MM | 588 | 0.9 (0.6-1.2) | .364 |
| 3-MM | 65 | 1.2 (0.7-2.2) | .458 |
| Patients in relapse† | |||
| 0-MM | 7 | 1.0 (0.2-4.4) | .977 |
| 1-MM | 77 | Reference | |
| 2-MM | 142 | 0.9 (0.5-1.5) | .693 |
| 3-MM | 28 | 1.4 (0.6-3.1) | .394 |
| Patients in remission† | |||
| 0-MM | 40 | 0.7 (0.3-1.5) | .359 |
| 1-MM | 228 | Reference | |
| 2-MM | 371 | 0.9 (0.6-1.4) | .662 |
| 3-MM | 32 | 1.5 (0.6-3.8) | .411 |
| Patients who engrafted | |||
| 0-MM | 47 | 0.7 (0.4-1.4) | .350 |
| 1-MM | 254 | Reference | |
| 2-MM | 418 | 1.0 (0.7-1.4) | .804 |
| 3-MM | 45 | 1.7 (0.9-3.4) | .108 |
| Variable . | n . | RR (95% Confidence interval) . | P . |
|---|---|---|---|
| All patients* | |||
| 0-MM | 56 | 0.7 (0.4-1.3) | .211 |
| 1-MM | 352 | Reference | |
| 2-MM | 588 | 0.9 (0.6-1.2) | .364 |
| 3-MM | 65 | 1.2 (0.7-2.2) | .458 |
| Patients in relapse† | |||
| 0-MM | 7 | 1.0 (0.2-4.4) | .977 |
| 1-MM | 77 | Reference | |
| 2-MM | 142 | 0.9 (0.5-1.5) | .693 |
| 3-MM | 28 | 1.4 (0.6-3.1) | .394 |
| Patients in remission† | |||
| 0-MM | 40 | 0.7 (0.3-1.5) | .359 |
| 1-MM | 228 | Reference | |
| 2-MM | 371 | 0.9 (0.6-1.4) | .662 |
| 3-MM | 32 | 1.5 (0.6-3.8) | .411 |
| Patients who engrafted | |||
| 0-MM | 47 | 0.7 (0.4-1.4) | .350 |
| 1-MM | 254 | Reference | |
| 2-MM | 418 | 1.0 (0.7-1.4) | .804 |
| 3-MM | 45 | 1.7 (0.9-3.4) | .108 |
MM indicates mismatch; and RR, relative risk.
Other predictive variables, such as advanced disease, diagnosis of JCML, and younger age (< 10 years), were associated with an increased risk of relapse. TNC, transplant center experience, year of transplant, and patient ethnicity were not predictive of relapse.
The subanalyses of those transplanted in relapse or remission excludes those with unknown disease status at time of transplantation and MDS.