Table 2

Percent reticulocytes and spleen weights, total bilirubin, and plasma iron levels by genotype

GenotypeSpleen weight, % body weightReticulocyte, %Total bilirubin, mg/dLPlasma iron, μg/dL
NOD-+/+ 0.35 ± 0.06 (8) 2.8 ± 0.8 (3) 0.63 ± 0.11 (7) 278.4 ± 59.5 (7) 
sph3J/sph3J 4.68 ± 0.96* (9) 88.4 ± 2.5* (4) 1.23 ± 0.18* (7) 485.7 ± 42.4* (7) 
B6-+/+ 0.27 ± 0.08 (4) 3.3 ± 1.5 (3) 0.51 ± 0.25 (6) 148.5 ± 32.8 (6) 
sph4J/sph4J 4.27 ± 1.07*; (17) 91.5 ± 1.1* (3) 1.87 ± 0.81* (15) 213.6 ± 65.5 (15) 
GenotypeSpleen weight, % body weightReticulocyte, %Total bilirubin, mg/dLPlasma iron, μg/dL
NOD-+/+ 0.35 ± 0.06 (8) 2.8 ± 0.8 (3) 0.63 ± 0.11 (7) 278.4 ± 59.5 (7) 
sph3J/sph3J 4.68 ± 0.96* (9) 88.4 ± 2.5* (4) 1.23 ± 0.18* (7) 485.7 ± 42.4* (7) 
B6-+/+ 0.27 ± 0.08 (4) 3.3 ± 1.5 (3) 0.51 ± 0.25 (6) 148.5 ± 32.8 (6) 
sph4J/sph4J 4.27 ± 1.07*; (17) 91.5 ± 1.1* (3) 1.87 ± 0.81* (15) 213.6 ± 65.5 (15) 

Number in parentheses indicates sample number. All values are reported as mean ± SD.

*

P < .001 vs control (+/+) mice.

P < .05 vs control (+/+) mice.

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