Table 4

Prognostic factors significant for EFS or OS

Prognostic factorTotal randomized
TG regimens
MP regimens
RelapseDeathRelapseDeathRelapseDeath
Age, y 1.53 1.58 1.64 1.86 1.44 1.33 
    Younger than 2, older than 5 vs 2-5 P = .001 P = .03 P = .02 P = .04 P = .02 P = .44 
Sex 1.5 1.15 1.2 1.09 1.4 1.2 
    Male vs female P = .002 P = .4 P = .25 P = .69 P = .002 P = .43 
CNS status 1.94 1.39 1.49 0.86 2.25 1.81 
    CNS-2 vs CNS-1 P = .001 P = .5 P = .46 P = .57 P = .001 P = .07 
WBC, ×109/L 1.6 1.85 1.72 1.77 1.6 1.91 
    20 or higher vs lower than 20 P < .001 P = .001 P = .003 P = .03 P = .003 P = .008 
Phenotype 1.35 1.3 1.13 1.45 1.54 1.25 
    T vs pre-B P = .2 P = .43 P = .75 P = .42 P = .14 P = .76 
Day-14 BM 2.2 1.9 2.68 2.3 1.9 1.56 
    M2 vs M1 P < .001 P = .005 P < .001 P = .006 P = .001 P = .19 
Prognostic factorTotal randomized
TG regimens
MP regimens
RelapseDeathRelapseDeathRelapseDeath
Age, y 1.53 1.58 1.64 1.86 1.44 1.33 
    Younger than 2, older than 5 vs 2-5 P = .001 P = .03 P = .02 P = .04 P = .02 P = .44 
Sex 1.5 1.15 1.2 1.09 1.4 1.2 
    Male vs female P = .002 P = .4 P = .25 P = .69 P = .002 P = .43 
CNS status 1.94 1.39 1.49 0.86 2.25 1.81 
    CNS-2 vs CNS-1 P = .001 P = .5 P = .46 P = .57 P = .001 P = .07 
WBC, ×109/L 1.6 1.85 1.72 1.77 1.6 1.91 
    20 or higher vs lower than 20 P < .001 P = .001 P = .003 P = .03 P = .003 P = .008 
Phenotype 1.35 1.3 1.13 1.45 1.54 1.25 
    T vs pre-B P = .2 P = .43 P = .75 P = .42 P = .14 P = .76 
Day-14 BM 2.2 1.9 2.68 2.3 1.9 1.56 
    M2 vs M1 P < .001 P = .005 P < .001 P = .006 P = .001 P = .19 

Data are relative hazard rates (RHR); P value log rank.

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