Table 3

Cox regression analysis

CovariateUnivariate
Multivariate
Hazard ratio (95% CI)PHazard ratio (95% CI)P
RFC80 AA versus GA/GG 0.50 (0.25-1.00) .046 0.56 (0.28-1.13) .10 
Phenotype, pre B versus T* 0.97 (0.51-1.87) .94  .94 
Copy no. of Chr21 higher than 2 versus 2 0.80 (0.46-1.39) .44  .71 
Risk group, high versus low 2.97 (1.90-4.63) < .001 2.86 (1.83-4.47) < .001 
Protocol, 2000 versus 1992 0.90 (0.55-1.48) .68  .32 
CovariateUnivariate
Multivariate
Hazard ratio (95% CI)PHazard ratio (95% CI)P
RFC80 AA versus GA/GG 0.50 (0.25-1.00) .046 0.56 (0.28-1.13) .10 
Phenotype, pre B versus T* 0.97 (0.51-1.87) .94  .94 
Copy no. of Chr21 higher than 2 versus 2 0.80 (0.46-1.39) .44  .71 
Risk group, high versus low 2.97 (1.90-4.63) < .001 2.86 (1.83-4.47) < .001 
Protocol, 2000 versus 1992 0.90 (0.55-1.48) .68  .32 

CI indicates confidence interval.

*

Low-risk patients were excluded from the model because no T-ALL were assigned to low-risk therapy.

If only relapse was considered as an event, then P = .13.

P value of covariate if included in the final model.

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