Table 1

Patients and studies

PatientsNo eventsRelapseDied before first HDMTXChange of protocol before first HDMTXSMNDead in CR
All patients 563 452 74 22 
All patients treated at Rigshospitalet 238 192 31 
Outcome study 500 422 70 
Toxicity study, first HDM course 123 110 15    
Toxicity study, all HDM courses 182 156 22   
PatientsNo eventsRelapseDied before first HDMTXChange of protocol before first HDMTXSMNDead in CR
All patients 563 452 74 22 
All patients treated at Rigshospitalet 238 192 31 
Outcome study 500 422 70 
Toxicity study, first HDM course 123 110 15    
Toxicity study, all HDM courses 182 156 22   

HDMTX indicates high-dose methotrexate; SMN, secondary malignancy; and CR, complete remission.

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