Patient characteristics
Characteristic . | All cases (n = 190)* . | DVT only (n = 155) . | Controls (n = 379) . |
---|---|---|---|
Male, n (%) | 80 (42) | 67 (43) | 160 (42) |
Median age, y (range) | 57 (19-90) | 59 (19-90) | 56 (18-93) |
Unprovoked VT, n (%) | 69 (36) | 51 (33) | NA |
Provoked VT, n (%) | 121 (64) | 102 (67) | NA |
OCP/HRT | 41 (22) | 31 (20) | 40 (11) |
Malignancy | 24 (13) | 22 (14) | 24 (6) |
Pregnancy/puerperium | 0 (0) | 0 (0) | 3 (1) |
Paralysis | 16 (8) | 15 (10) | 30 (8) |
Recent trauma | 26 (14) | 22 (14) | 53 (14) |
Surgery/bedridden | 30 (16) | 29 (19) | 31 (8) |
Hospitalization | 35 (18) | 33 (21) | 48 (13) |
Long-distance travel | 30 (16) | 23 (15) | 43 (11) |
Use of thyroxine substitution therapy, n (%) | 6 (3) | 5 (3) | 7 (2) |
Autoimmune hypothyroidism | 1 (1) | 1 (1) | 2 (1) |
Central hypothyroidism | 0 (0) | 0 (0) | 1 (0.3) |
Iatrogenic hypothyroidism | 3 (2) | 3 (2) | 0 (0) |
Hypothyroidism unknown cause | 2 (1) | 1 (1) | 4 (1) |
Use of antithyroidal agents, n (%) | 1 (0.5) | 0 (0) | 0 (0) |
Characteristic . | All cases (n = 190)* . | DVT only (n = 155) . | Controls (n = 379) . |
---|---|---|---|
Male, n (%) | 80 (42) | 67 (43) | 160 (42) |
Median age, y (range) | 57 (19-90) | 59 (19-90) | 56 (18-93) |
Unprovoked VT, n (%) | 69 (36) | 51 (33) | NA |
Provoked VT, n (%) | 121 (64) | 102 (67) | NA |
OCP/HRT | 41 (22) | 31 (20) | 40 (11) |
Malignancy | 24 (13) | 22 (14) | 24 (6) |
Pregnancy/puerperium | 0 (0) | 0 (0) | 3 (1) |
Paralysis | 16 (8) | 15 (10) | 30 (8) |
Recent trauma | 26 (14) | 22 (14) | 53 (14) |
Surgery/bedridden | 30 (16) | 29 (19) | 31 (8) |
Hospitalization | 35 (18) | 33 (21) | 48 (13) |
Long-distance travel | 30 (16) | 23 (15) | 43 (11) |
Use of thyroxine substitution therapy, n (%) | 6 (3) | 5 (3) | 7 (2) |
Autoimmune hypothyroidism | 1 (1) | 1 (1) | 2 (1) |
Central hypothyroidism | 0 (0) | 0 (0) | 1 (0.3) |
Iatrogenic hypothyroidism | 3 (2) | 3 (2) | 0 (0) |
Hypothyroidism unknown cause | 2 (1) | 1 (1) | 4 (1) |
Use of antithyroidal agents, n (%) | 1 (0.5) | 0 (0) | 0 (0) |
DVT indicates deep venous thrombosis; VT, venous thrombosis; NA, not applicable; OCP, oral contraceptive pill; and HRT, hormone replacement therapy.
All patients with VT (DVT, calf vein thrombosis, or thrombophlebitis).