Table 3

Causes of death in CR in patients included in APL93 trial

nCause%
During consolidation courses 23 Sepsis, n = 16 70 
  Bleeding, n = 1 
  Heart failure, n = 1 
  Unknown, n = 4 18 
  Tumor unrelated to APL,* n = 1 
During the maintenance treatment phase 10 Sepsis, n = 6 60 
  Heart failure, n = 2 20 
  Sudden death, n = 1 10 
  Unknown, n = 1 10 
After maintenance 26 Sepsis, n = 1 
  Other tumor, n = 8 30 
  Heart failure, n = 2 
  Sudden death, n = 2 
  Liver cirrhosis, n = 1 
  MDS, n = 1 
  Unrelated to APL, n = 11 42 
nCause%
During consolidation courses 23 Sepsis, n = 16 70 
  Bleeding, n = 1 
  Heart failure, n = 1 
  Unknown, n = 4 18 
  Tumor unrelated to APL,* n = 1 
During the maintenance treatment phase 10 Sepsis, n = 6 60 
  Heart failure, n = 2 20 
  Sudden death, n = 1 10 
  Unknown, n = 1 10 
After maintenance 26 Sepsis, n = 1 
  Other tumor, n = 8 30 
  Heart failure, n = 2 
  Sudden death, n = 2 
  Liver cirrhosis, n = 1 
  MDS, n = 1 
  Unrelated to APL, n = 11 42 
*

Relapse of a carcinoma which was in complete remission at the time of inclusion.

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