Relationship between SNP mapping within 25 kb of EPOR and BCP-ALL risk
| SNP . | Location, bp . | Ancestral allele . | ETV6-RUNX1-positive cases . | Hyperdiploid cases . | Other cases . | |||
|---|---|---|---|---|---|---|---|---|
| Odds ratio . | P . | Odds ratio . | P . | Odds ratio . | P . | |||
| rs7251786 | 11 325 879 | T | 1.16 | .264 | 1.04 | .675 | 0.94 | .416 |
| rs318699 | 11 362 240 | G | 1.11 | .423 | 1.12 | .207 | 1.02 | .818 |
| rs4804164 | 11 363 291 | G | 0.58 | .008 | 0.92 | .588 | 0.97 | .838 |
| rs2291516 | 11 369 177 | G | 0.83 | .409 | 1.10 | .526 | 1.03 | .827 |
| rs317913 | 11 373 314 | C | 0.60 | .019 | 0.97 | .850 | 0.94 | .680 |
| SNP . | Location, bp . | Ancestral allele . | ETV6-RUNX1-positive cases . | Hyperdiploid cases . | Other cases . | |||
|---|---|---|---|---|---|---|---|---|
| Odds ratio . | P . | Odds ratio . | P . | Odds ratio . | P . | |||
| rs7251786 | 11 325 879 | T | 1.16 | .264 | 1.04 | .675 | 0.94 | .416 |
| rs318699 | 11 362 240 | G | 1.11 | .423 | 1.12 | .207 | 1.02 | .818 |
| rs4804164 | 11 363 291 | G | 0.58 | .008 | 0.92 | .588 | 0.97 | .838 |
| rs2291516 | 11 369 177 | G | 0.83 | .409 | 1.10 | .526 | 1.03 | .827 |
| rs317913 | 11 373 314 | C | 0.60 | .019 | 0.97 | .850 | 0.94 | .680 |
Odds ratios were calculated with the ancestral allele as the reference allele, and P values are from the Cochran-Armitage trend test.
SNP indicates single nucleotide polymorphism; and BCP-ALL, B-cell precursor acute lymphoblastic leukemia.