List of 7 ROH with frequency of more than 25% in the controls
| ROH . | Chromosome . | Start, bp . | End, bp . | Length, bp . | No. of SNPs . | No. (%) of controls . | iHSmax* . | Tajima Dmax* . | Fstmax* . | No. of deletions/duplications/hotspots . |
|---|---|---|---|---|---|---|---|---|---|---|
| ROH92 | 3p12.3-3q13.11 | 77 828 854 | 106 110 833 | 28 281 979 | 1623 | 872 (37.0) | 2.24 | 2.90 | 0.79 | 4/4/100 |
| ROH162 | 6p22.2-6p21.31 | 24 213 309 | 36 712 176 | 12 498 867 | 1971 | 835 (35.4) | 2.84 | 2.10 | 0.86 | 3/8/61 |
| ROH283 | 11p11.2-11q12.2 | 45 131 106 | 60 672 543 | 15 541 437 | 801 | 768 (32.6) | 2.31 | 2.59 | 0.80 | 5/5/32 |
| ROH218 | 8p11.21-8q11.23 | 41 842 707 | 55 590 142 | 13 747 435 | 651 | 760 (32.3) | 3.80 | 2.20 | 0.84 | 5/6/53 |
| ROH62 | 2q21.2-2q22.1 | 134 030 848 | 142 232 977 | 8 202 129 | 822 | 635 (26.9) | 4.25 | 2.33 | 0.68 | 0/2/65 |
| ROH136 | 5p13.1-5q11.2 | 39 299 418 | 53 546 258 | 14 246 840 | 919 | 608 (25.8) | 1.75 | 2.30 | 0.70 | 5/2/44 |
| ROH351 | 15q23-15q25.1 | 69 391 304 | 76 490 686 | 7 099 382 | 571 | 599 (25.4) | 2.26 | 3.15 | 0.72 | 5/1/37 |
| ROH . | Chromosome . | Start, bp . | End, bp . | Length, bp . | No. of SNPs . | No. (%) of controls . | iHSmax* . | Tajima Dmax* . | Fstmax* . | No. of deletions/duplications/hotspots . |
|---|---|---|---|---|---|---|---|---|---|---|
| ROH92 | 3p12.3-3q13.11 | 77 828 854 | 106 110 833 | 28 281 979 | 1623 | 872 (37.0) | 2.24 | 2.90 | 0.79 | 4/4/100 |
| ROH162 | 6p22.2-6p21.31 | 24 213 309 | 36 712 176 | 12 498 867 | 1971 | 835 (35.4) | 2.84 | 2.10 | 0.86 | 3/8/61 |
| ROH283 | 11p11.2-11q12.2 | 45 131 106 | 60 672 543 | 15 541 437 | 801 | 768 (32.6) | 2.31 | 2.59 | 0.80 | 5/5/32 |
| ROH218 | 8p11.21-8q11.23 | 41 842 707 | 55 590 142 | 13 747 435 | 651 | 760 (32.3) | 3.80 | 2.20 | 0.84 | 5/6/53 |
| ROH62 | 2q21.2-2q22.1 | 134 030 848 | 142 232 977 | 8 202 129 | 822 | 635 (26.9) | 4.25 | 2.33 | 0.68 | 0/2/65 |
| ROH136 | 5p13.1-5q11.2 | 39 299 418 | 53 546 258 | 14 246 840 | 919 | 608 (25.8) | 1.75 | 2.30 | 0.70 | 5/2/44 |
| ROH351 | 15q23-15q25.1 | 69 391 304 | 76 490 686 | 7 099 382 | 571 | 599 (25.4) | 2.26 | 3.15 | 0.72 | 5/1/37 |
Chromosomal coordinates were derived from the National Center for Biotechnology Information, build 36.
ROH indicates regions of homozygosity; and SNP, single nucleotide polymorphism.
Maximal values for several metrics of positive selection, derived from Haplotter (http://hg-wen.uchicago.edu/selection/haplotter.htm). The number of deletions, duplications, and recombination hotspots are derived from HapMap release 27 (http://hapmap.org).