Hematologic and serum parameters of pregnant Tmprss6+/+ and Tmprss6+/− mice at gestational day 18.5
| Genotype . | Whole blood . | Serum . | ||||||
|---|---|---|---|---|---|---|---|---|
| RBC, ×1012/L . | Hgb, g/L . | Hct . | MCV, ×10−15L . | MCH, pg . | RDW, % . | Iron, μM . | Tf sat, % . | |
| Tmprss6+/+ | 8.4 ± 0.2*† | 137 ± 4 | 0.417 ± 0.009 | 49.6 ± 0.5*‡ | 16.2 ± 0.4† | 19.7 ± 0.4* | 24.3 ± 5.2 | 57 ± 9 |
| Tmprss6+/− | 8.5 ± 0.1† | 137 ± 3 | 0.412 ± 0.007 | 48.3 ± 0.3‡ | 16.0 ± 0.1‡ | 19.5 ± 0.5 | 23.9 ± 3.3 | 59 ± 7 |
| Genotype . | Whole blood . | Serum . | ||||||
|---|---|---|---|---|---|---|---|---|
| RBC, ×1012/L . | Hgb, g/L . | Hct . | MCV, ×10−15L . | MCH, pg . | RDW, % . | Iron, μM . | Tf sat, % . | |
| Tmprss6+/+ | 8.4 ± 0.2*† | 137 ± 4 | 0.417 ± 0.009 | 49.6 ± 0.5*‡ | 16.2 ± 0.4† | 19.7 ± 0.4* | 24.3 ± 5.2 | 57 ± 9 |
| Tmprss6+/− | 8.5 ± 0.1† | 137 ± 3 | 0.412 ± 0.007 | 48.3 ± 0.3‡ | 16.0 ± 0.1‡ | 19.5 ± 0.5 | 23.9 ± 3.3 | 59 ± 7 |
Complete blood counts were measured from whole blood of, and iron and transferrin saturation were measured from serum of, pregnant Tmprss6+/+ (n = 5) and Tmprss6+/− (n = 7) mice. Data are presented as mean ± SEM.
RBC indicates red blood cell count; Hgb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; RDW, red cell distribution width; and Tf sat, transferrin saturation.
P < .05 compared with nonpregnant Tmprss6+/+ female mice (from Table 1).
P < .05 compared with nonpregnant Tmprss6+/− female mice (from Table 1).
P < .001 compared with nonpregnant Tmprss6+/− female mice (from Table 1).