Linear regression models assessing the relationship of IL-6 and CRP with serum iron, after adjusting for confounders
| Variable . | Model 1 . | Model 2 . | Model 3* . | |||
|---|---|---|---|---|---|---|
| Beta (SE) . | P . | Beta (SE) . | P . | Beta (SE) . | P . | |
| Age, y | 0.09 (0.15) | .52 | 0.10 (0.15) | .49 | 0.11 (0.15) | .47 |
| Sex | −6.48 (2.16) | .003 | −5.63 (2.18) | .01 | −4.37 (2.30) | .06 |
| Body mass index, kg/m2 | −0.04 (0.25) | .87 | −0.02 (0.25) | .95 | 0.15 (0.25) | .55 |
| Hemoglobin, g/dL | 7.8 (0.8) | < .001 | 7.5 (0.8) | < .001 | 6.3 (1) | < .001 |
| Loge interleukin-6, pg/mL | −2.99 (1.84) | .10 | −2.98 (1.83) | .10 | −1.91 (1.80) | .29 |
| Loge C-reactive protein, mg/L | −6.45 (1.07) | < .001 | −6.39 (1.07) | < .001 | −6.96 (1.03) | < .001 |
| Loge hepcidin, ng/mg creatinine | 1.00 (0.43) | .02 | 0.04 (0.45) | .92 | ||
| Variable . | Model 1 . | Model 2 . | Model 3* . | |||
|---|---|---|---|---|---|---|
| Beta (SE) . | P . | Beta (SE) . | P . | Beta (SE) . | P . | |
| Age, y | 0.09 (0.15) | .52 | 0.10 (0.15) | .49 | 0.11 (0.15) | .47 |
| Sex | −6.48 (2.16) | .003 | −5.63 (2.18) | .01 | −4.37 (2.30) | .06 |
| Body mass index, kg/m2 | −0.04 (0.25) | .87 | −0.02 (0.25) | .95 | 0.15 (0.25) | .55 |
| Hemoglobin, g/dL | 7.8 (0.8) | < .001 | 7.5 (0.8) | < .001 | 6.3 (1) | < .001 |
| Loge interleukin-6, pg/mL | −2.99 (1.84) | .10 | −2.98 (1.83) | .10 | −1.91 (1.80) | .29 |
| Loge C-reactive protein, mg/L | −6.45 (1.07) | < .001 | −6.39 (1.07) | < .001 | −6.96 (1.03) | < .001 |
| Loge hepcidin, ng/mg creatinine | 1.00 (0.43) | .02 | 0.04 (0.45) | .92 | ||
Model 3 adjusted for iron intake, energy intake, sTFR/log(ferritin) ratio, and major chronic diseases.