Lugano and Manchester scores for gastrointestinal lymphomas
| . | Definition . |
|---|---|
| Lugano score | |
| Stage I | Confined to gastrointestinal tract (single primary or multiple noncontiguous sites of disease) |
| Stage II1* | Local abdominal nodal involvement |
| Stage II2* | Distant abdominal nodal involvement |
| Stage IIE | Serosal penetration to involve adjacent organ or tissues |
| Stage IV | Disseminated extranodal involvement or supradiaphragmatic nodal involvement |
| Manchester score | |
| Stage Ia | Tumour confined to one area of the gastrointestinal tract without penetration of the serosa |
| Stage Ib | Multiple tumors confined to the gastrointestinal tract without penetration of the serosa |
| Stage IIa | Tumor with local nodes histologically involved (gastric or mesenteric) |
| Stage IIb | Tumor with perforation and/or adherence to adjacent structures |
| Stage IIc | Tumor with perforation and peritonitis |
| Stage III | Tumor with widespread nodal involvement (paraaortic or more distant nodes) |
| Stage IV | Disseminated disease involving extralymphatic tissues not adjacent to the tumor (eg, liver, bone marrow, bone, lung, etc) |
| . | Definition . |
|---|---|
| Lugano score | |
| Stage I | Confined to gastrointestinal tract (single primary or multiple noncontiguous sites of disease) |
| Stage II1* | Local abdominal nodal involvement |
| Stage II2* | Distant abdominal nodal involvement |
| Stage IIE | Serosal penetration to involve adjacent organ or tissues |
| Stage IV | Disseminated extranodal involvement or supradiaphragmatic nodal involvement |
| Manchester score | |
| Stage Ia | Tumour confined to one area of the gastrointestinal tract without penetration of the serosa |
| Stage Ib | Multiple tumors confined to the gastrointestinal tract without penetration of the serosa |
| Stage IIa | Tumor with local nodes histologically involved (gastric or mesenteric) |
| Stage IIb | Tumor with perforation and/or adherence to adjacent structures |
| Stage IIc | Tumor with perforation and peritonitis |
| Stage III | Tumor with widespread nodal involvement (paraaortic or more distant nodes) |
| Stage IV | Disseminated disease involving extralymphatic tissues not adjacent to the tumor (eg, liver, bone marrow, bone, lung, etc) |
Combinations such as II1 E and II2 E are also possible.