Morbidity and mortality after transplantation
| . | Related, no. . | Unrelated, no. . | Combined no. (%) . |
|---|---|---|---|
| Nonfatal toxicity up to day 100* | |||
| ALT elevation, grade IV | 8 | 5 | 13 (11) |
| AST elevation, grade IV | 4 | 2 | 6 (5) |
| Bilirubin elevation, grade IV | 4 | 4 | 8 (7) |
| Serum creatinine, grade III | 3 | 3 | 6 (5) |
| Reversible VOD | 7 | 1 | 8 (7) |
| Hemorrhagic cystitis | 1 | 11 | 12 (10) |
| Pericardial effusion | 3 | 0 | 3 (3) |
| Subdural hematoma | 1 | 0 | 1 (1) |
| Cause of death | |||
| Related to relapse or progression | 21 | 10 | 31 (26) |
| Related to transplantation | |||
| Graft failure | 0 | 1 | 1 (1) |
| VOD | 2 | 0 | 2 (2) |
| Noninfectious pneumonia | 1 | 1 | 2 (2) |
| Sepsis/bacterial infection | 2 | 1 | 3 (3) |
| Hemorrhage | 2 | 2 | 4 (3) |
| Refractory GVHD | 2 | 1 | 3 (3) |
| Multisystem organ failure | 3 | 2 | 5 (4) |
| . | Related, no. . | Unrelated, no. . | Combined no. (%) . |
|---|---|---|---|
| Nonfatal toxicity up to day 100* | |||
| ALT elevation, grade IV | 8 | 5 | 13 (11) |
| AST elevation, grade IV | 4 | 2 | 6 (5) |
| Bilirubin elevation, grade IV | 4 | 4 | 8 (7) |
| Serum creatinine, grade III | 3 | 3 | 6 (5) |
| Reversible VOD | 7 | 1 | 8 (7) |
| Hemorrhagic cystitis | 1 | 11 | 12 (10) |
| Pericardial effusion | 3 | 0 | 3 (3) |
| Subdural hematoma | 1 | 0 | 1 (1) |
| Cause of death | |||
| Related to relapse or progression | 21 | 10 | 31 (26) |
| Related to transplantation | |||
| Graft failure | 0 | 1 | 1 (1) |
| VOD | 2 | 0 | 2 (2) |
| Noninfectious pneumonia | 1 | 1 | 2 (2) |
| Sepsis/bacterial infection | 2 | 1 | 3 (3) |
| Hemorrhage | 2 | 2 | 4 (3) |
| Refractory GVHD | 2 | 1 | 3 (3) |
| Multisystem organ failure | 3 | 2 | 5 (4) |
ALT indicates alanine aminotransferase; and AST, aspartate aminotransferase.
Only highest-grade toxicities are presented.