Table 5

Details of secondary transplants

SampleFractionSecondary recipients*Tertiary recipients*Time in vivo, weeks
CD34CD38+ 4/4 5/5 31 
CD34CD38 2/2 NT 26 
CD34CD38+ 5/5 5/5 12 
CD34CD38+ 3/3 NT 34 
CD34CD38 1/1 NT 34 
17 CD34CD38+ 3/3 NT 24 
17 CD34CD38 3/3 NT 24 
17 CD34+CD38+ 3/3 NT 18 
17 CD34+CD38 1/1 NT 25 
26 CD34CD38+ 3/3 NT 24 
26 CD34CD38 4/4 NT 24 
26 CD34+CD38+ 4/4 NT 24 
26 CD34+CD38 0/1 NT 24 
24 CD34CD38+ 1/1 NT 24 
24 CD34CD38 Mouse died NT 24 
24 CD34+CD38+ 1/1 NT 24 
24 CD34+CD38 1/1 NT 24 
SampleFractionSecondary recipients*Tertiary recipients*Time in vivo, weeks
CD34CD38+ 4/4 5/5 31 
CD34CD38 2/2 NT 26 
CD34CD38+ 5/5 5/5 12 
CD34CD38+ 3/3 NT 34 
CD34CD38 1/1 NT 34 
17 CD34CD38+ 3/3 NT 24 
17 CD34CD38 3/3 NT 24 
17 CD34+CD38+ 3/3 NT 18 
17 CD34+CD38 1/1 NT 25 
26 CD34CD38+ 3/3 NT 24 
26 CD34CD38 4/4 NT 24 
26 CD34+CD38+ 4/4 NT 24 
26 CD34+CD38 0/1 NT 24 
24 CD34CD38+ 1/1 NT 24 
24 CD34CD38 Mouse died NT 24 
24 CD34+CD38+ 1/1 NT 24 
24 CD34+CD38 1/1 NT 24 

NT indicates not tested.

*

Data for secondary and tertiary recipients are reported as mice with AML/mice transplanted.

Time in vivo refers to the time from transplantation in the primary recipient to the termination of the final recipient. Sample 7 is very aggressive clinically and mice became sick due to leukemia 3 to 5 weeks after transplantation, hence the relatively short duration.

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