Selected differentially expressed genes in LSK cells (leukemic dtg/controls)
| Gene symbol: name . | Probe set ID . | Fold change . | P . |
|---|---|---|---|
| Differentiation | |||
| RelB: avian reticuloendotheliosis viral (v-rel) oncogene-related B | 1417856_at | 2.85 | .048 |
| FcgR2b: Fc receptor, IgG, low affinity IIb | 1451941_a_at | 2.79 | .005 |
| Ccr2: chemokine (C-C motif) receptor 2 | 1421186_at | 2.5 | .049 |
| Itgax: integrin α x (CD11c/CD18) | 1419128_at | 2.21 | .011 |
| CD48: CD48 molecule | 1427301_at | 2.07 | .037 |
| SOCS3: suppressor of cytokine signaling 3 | 1416576_at | 2.03 | .024 |
| Irf8: interferon regulatory factor 8 | 1448452_at | 1.8 | .049 |
| Csf1r: colony-stimulating factor 1 receptor | 1423593_a_at | 1.6 | .045 |
| Hba-a1: hemoglobin-α, adult chain 1 | 1452757_s_at | −6.59 | .021 |
| β-Globin | 1427866_x_at | −3.44 | .019 |
| HoxB8: homeobox B8 | 1452493_s_at | −1.57 | .005 |
| Proliferation | |||
| Ccnd1: cyclin D1 | 1417419_at | 1.98 | .013 |
| Cdkn1a: cyclin-dependent kinase inhibitor 1A (P21) | 1424638_at | 1.89 | .009 |
| Rras2/TC21: related RAS viral oncogene homolog 2 | 1417398_at | 1.86 | .020 |
| Set: SET translocation | 1421819_a_at | 1.85 | .022 |
| Bin1: bridging integrator 1 | 1423618_at | −35.55 | .035 |
| Ptpn14: protein tyrosine phosphatase, nonreceptor type 14 | 1436442_at | −1.59 | .033 |
| Self-renewal | |||
| Lifr: leukemia inhibitory factor receptor | 1450207_at | −1.80 | .014 |
| Evi1: ectropic viral integration site 1 | 1438325_at | −1.76 | .039 |
| Mpl: myeloproliferative leukemia virus oncogene | 1421461_at | −1.53 | .010 |
| Gene symbol: name . | Probe set ID . | Fold change . | P . |
|---|---|---|---|
| Differentiation | |||
| RelB: avian reticuloendotheliosis viral (v-rel) oncogene-related B | 1417856_at | 2.85 | .048 |
| FcgR2b: Fc receptor, IgG, low affinity IIb | 1451941_a_at | 2.79 | .005 |
| Ccr2: chemokine (C-C motif) receptor 2 | 1421186_at | 2.5 | .049 |
| Itgax: integrin α x (CD11c/CD18) | 1419128_at | 2.21 | .011 |
| CD48: CD48 molecule | 1427301_at | 2.07 | .037 |
| SOCS3: suppressor of cytokine signaling 3 | 1416576_at | 2.03 | .024 |
| Irf8: interferon regulatory factor 8 | 1448452_at | 1.8 | .049 |
| Csf1r: colony-stimulating factor 1 receptor | 1423593_a_at | 1.6 | .045 |
| Hba-a1: hemoglobin-α, adult chain 1 | 1452757_s_at | −6.59 | .021 |
| β-Globin | 1427866_x_at | −3.44 | .019 |
| HoxB8: homeobox B8 | 1452493_s_at | −1.57 | .005 |
| Proliferation | |||
| Ccnd1: cyclin D1 | 1417419_at | 1.98 | .013 |
| Cdkn1a: cyclin-dependent kinase inhibitor 1A (P21) | 1424638_at | 1.89 | .009 |
| Rras2/TC21: related RAS viral oncogene homolog 2 | 1417398_at | 1.86 | .020 |
| Set: SET translocation | 1421819_a_at | 1.85 | .022 |
| Bin1: bridging integrator 1 | 1423618_at | −35.55 | .035 |
| Ptpn14: protein tyrosine phosphatase, nonreceptor type 14 | 1436442_at | −1.59 | .033 |
| Self-renewal | |||
| Lifr: leukemia inhibitory factor receptor | 1450207_at | −1.80 | .014 |
| Evi1: ectropic viral integration site 1 | 1438325_at | −1.76 | .039 |
| Mpl: myeloproliferative leukemia virus oncogene | 1421461_at | −1.53 | .010 |
Expression pattern was analyzed in LSK cells of 3 leukemic mice vs 3 controls.