Table 1 Phenotype of mice transplanted... | American Society of Hematology

Table 1

Phenotype of mice transplanted with unfractionated BM or FACS-purified LSK cells

	Unfractionated BM		LSK cells
	Control	SCLtTA/BCR-ABL	Control	SCLtTA/BCR-ABL
Total no. of transplanted cells per mouse	1 × 10⁶	1 × 10⁶	1200 (+1 × 10⁵ wt)	1200 (+1 × 10⁵ wt)
No. of transplanted LSK cells per mouse	230	398	1200	1200
WBCs, ×10⁹/L	5.2 ± 0.09	18.8 ± 9.9*	4.82 ± 1.2	5.88 ± 1.9†
Gr-1⁺CD11b⁺ cells in the PB, percentage	20 ± 6.1	68.8 ± 14.52*	28.5 ± 14.8	53.6 ± 16.1
Absolute no. of Gr-1⁺CD11b⁺ cells in the PB, ×10³/μL	0.9 ± 0.3	12.7 ± 7.4*	1.5 ± 1.1	3.4 ± 2.1†
Moribund appearance after BM transplantation, wk	Never	8	Never	11

	Unfractionated BM		LSK cells
	Control	SCLtTA/BCR-ABL	Control	SCLtTA/BCR-ABL
Total no. of transplanted cells per mouse	1 × 10⁶	1 × 10⁶	1200 (+1 × 10⁵ wt)	1200 (+1 × 10⁵ wt)
No. of transplanted LSK cells per mouse	230	398	1200	1200
WBCs, ×10⁹/L	5.2 ± 0.09	18.8 ± 9.9*	4.82 ± 1.2	5.88 ± 1.9†
Gr-1⁺CD11b⁺ cells in the PB, percentage	20 ± 6.1	68.8 ± 14.52*	28.5 ± 14.8	53.6 ± 16.1
Absolute no. of Gr-1⁺CD11b⁺ cells in the PB, ×10³/μL	0.9 ± 0.3	12.7 ± 7.4*	1.5 ± 1.1	3.4 ± 2.1†
Moribund appearance after BM transplantation, wk	Never	8	Never	11

WBC and Gr-1⁺CD11b⁺ cells were assessed 7 weeks after transplantation.

P < .05 vs control group.

P < .05 vs ufBM SCLtTA/BCR-ABL group. ufBM, n = 5 (stg) or 4 (dtg); LSK, n = 4 each.