Nucleotide sequences of clonal TCRVβ from WM patients PBMCs (patient nos. 4-6)
| No. . | Chain and sequence . | ||||
|---|---|---|---|---|---|
| 3′ V . | N(D)N . | 5′ J . | V (D) J sequence . | CDR3 length, aa . | |
| 4 | TGTGCCTGGAG | GGGGACAGGGTTTTTG | TATGGCTACACCTTC | Vβ20 Dβ1Jβ1.2 | 12 |
| 5 | TGTGCCAGCAGCTTAG | TCCCCGACGGACCGGGACTAGCGGGAGGGCCCAT | CTCCTACAATGAGCAGTTCTTC | Vβ21.3Dβ2Jβ2.1 | 22 |
| 6 | TGTGCCAGCAGCTTA | CCGGGGAACGTTGG | CGAGCAGTACTTC | Vβ23Dβ2Jβ2.7 | 12 |
| No. . | Chain and sequence . | ||||
|---|---|---|---|---|---|
| 3′ V . | N(D)N . | 5′ J . | V (D) J sequence . | CDR3 length, aa . | |
| 4 | TGTGCCTGGAG | GGGGACAGGGTTTTTG | TATGGCTACACCTTC | Vβ20 Dβ1Jβ1.2 | 12 |
| 5 | TGTGCCAGCAGCTTAG | TCCCCGACGGACCGGGACTAGCGGGAGGGCCCAT | CTCCTACAATGAGCAGTTCTTC | Vβ21.3Dβ2Jβ2.1 | 22 |
| 6 | TGTGCCAGCAGCTTA | CCGGGGAACGTTGG | CGAGCAGTACTTC | Vβ23Dβ2Jβ2.7 | 12 |
TCRVβ indicates T-cell receptor Vβ; WM, Waldenstrom macroglobulinemia; PBMCs, peripheral blood mononuclear cells; and aa, amino acid.