Comparison of clinical characteristics for JMML patients with and without c-Cbl mutation
| Variable . | With c-Cbl mutation, n = 5 . | Without c-Cbl mutation, n = 44 . | P . |
|---|---|---|---|
| Median age at diagnosis, mo (range) | 12 (8-15) | 29 (1-75) | .037 |
| Median HbF, % (range) | 3.5 (2.0-7.6) | 24.9 (1.0-62.0) | .02 |
| Variable . | With c-Cbl mutation, n = 5 . | Without c-Cbl mutation, n = 44 . | P . |
|---|---|---|---|
| Median age at diagnosis, mo (range) | 12 (8-15) | 29 (1-75) | .037 |
| Median HbF, % (range) | 3.5 (2.0-7.6) | 24.9 (1.0-62.0) | .02 |
Other variables studied (sex, hemoglobin level, white blood cell count, platelet count, monocyte percentage in peripheral blood, and metaphase cytogenetic abnormalities) do not show statistical significance.
HbF indicates hemoglobin F.