Table 2 Phase 1–related adverse events... | American Society of Hematology

Table 2

Phase 1–related adverse events by grade

Adverse event	Cohort 1 (n = 6)		Cohort 2 (n = 7)		Total (n = 13)
Adverse event	%	Grade 3/4, %	%	Grade3/4, %	%	Grade 3/4, %
Diarrhea	83	17	71	0	77	8
Fatigue	33	0	43	14	39	8
Leukopenia	50	33	14	14	31	23
Hypertension	0	0	57	0	31	0
Neutropenia	33	33	14	14	23	23
Anemia	50	50	0	0	23	23
Asthenia	17	17	14	0	15	8
Nausea	0	0	29	0	15	0
Dyspepsia	0	0	29	0	15	0
Thrombocytopenia	17	0	14	0	15	0
Headache	0	0	29	0	15	0

Adverse event	Cohort 1 (n = 6)		Cohort 2 (n = 7)		Total (n = 13)
Adverse event	%	Grade 3/4, %	%	Grade3/4, %	%	Grade 3/4, %
Diarrhea	83	17	71	0	77	8
Fatigue	33	0	43	14	39	8
Leukopenia	50	33	14	14	31	23
Hypertension	0	0	57	0	31	0
Neutropenia	33	33	14	14	23	23
Anemia	50	50	0	0	23	23
Asthenia	17	17	14	0	15	8
Nausea	0	0	29	0	15	0
Dyspepsia	0	0	29	0	15	0
Thrombocytopenia	17	0	14	0	15	0
Headache	0	0	29	0	15	0