Univariate analysis of cumulative incidence of HSCT outcome in association with HPSE gene SNP combinations
| Outcome . | SNP combinations . | Cumulative incidence, % . | 95% CI for cumulative incidence . | P . |
|---|---|---|---|---|
| Chronic GVHD limited | Recipient | .69 | ||
| HR | 34.6 | 24.0-49.7 | ||
| MR | 49.3 | 40.3-60.3 | ||
| LR | 51.6 | 41.1-64.9 | ||
| Donor | .16 | |||
| HR | 35.7 | 24.9-51.2 | ||
| MR | 44.6 | 35.9-55.5 | ||
| LR | 59.4 | 46.7-75.4 | ||
| Chronic GVHD extensive | Recipient | < .001 | ||
| HR | 30.9 | 20.8-45.9 | ||
| MR | 14.3 | 8.8-23.3 | ||
| LR | 9.9 | 4.9-20.0 | ||
| Donor | .37 | |||
| HR | 24.1 | 15.0-38.8 | ||
| MR | 16.8 | 10.9-26.0 | ||
| LR | 12.5 | 5.9-26.5 | ||
| TRM | Recipient | .01 | ||
| HR | 30.0 | 22.8-39.4 | ||
| MR | 17.5 | 12.7-24.1 | ||
| LR | 19.0 | 13.0-27.6 | ||
| Donor | .33 | |||
| HR | 15.7 | 9.5-25.8 | ||
| MR | 21.2 | 16.0-28.2 | ||
| LR | 23.8 | 16.8-33.7 | ||
| Relapse | Recipient | .93 | ||
| HR | 40.2 | 32.0-50.6 | ||
| MR | 50.1 | 42.9-58.4 | ||
| LR | 46.3 | 37.5-57.0 | ||
| Donor | .38 | |||
| HR | 45.2 | 34.3-56.8 | ||
| MR | 50.7 | 43.6-58.9 | ||
| LR | 42.8 | 33.9-54.1 |
| Outcome . | SNP combinations . | Cumulative incidence, % . | 95% CI for cumulative incidence . | P . |
|---|---|---|---|---|
| Chronic GVHD limited | Recipient | .69 | ||
| HR | 34.6 | 24.0-49.7 | ||
| MR | 49.3 | 40.3-60.3 | ||
| LR | 51.6 | 41.1-64.9 | ||
| Donor | .16 | |||
| HR | 35.7 | 24.9-51.2 | ||
| MR | 44.6 | 35.9-55.5 | ||
| LR | 59.4 | 46.7-75.4 | ||
| Chronic GVHD extensive | Recipient | < .001 | ||
| HR | 30.9 | 20.8-45.9 | ||
| MR | 14.3 | 8.8-23.3 | ||
| LR | 9.9 | 4.9-20.0 | ||
| Donor | .37 | |||
| HR | 24.1 | 15.0-38.8 | ||
| MR | 16.8 | 10.9-26.0 | ||
| LR | 12.5 | 5.9-26.5 | ||
| TRM | Recipient | .01 | ||
| HR | 30.0 | 22.8-39.4 | ||
| MR | 17.5 | 12.7-24.1 | ||
| LR | 19.0 | 13.0-27.6 | ||
| Donor | .33 | |||
| HR | 15.7 | 9.5-25.8 | ||
| MR | 21.2 | 16.0-28.2 | ||
| LR | 23.8 | 16.8-33.7 | ||
| Relapse | Recipient | .93 | ||
| HR | 40.2 | 32.0-50.6 | ||
| MR | 50.1 | 42.9-58.4 | ||
| LR | 46.3 | 37.5-57.0 | ||
| Donor | .38 | |||
| HR | 45.2 | 34.3-56.8 | ||
| MR | 50.7 | 43.6-58.9 | ||
| LR | 42.8 | 33.9-54.1 |