Table 1

General characteristics of the study population

Control patients (n = 334)Patients with provoked PE (n = 259)Patients with unprovoked PE (n = 95)
Sex (female), %* 211 (63) 137 (53) 49 (55) 
Age, y (mean ± SD)* 48 ± 17 52 ± 18 55 ± 17 
History of arterial cardiovascular events, n (%) 40 (12) 38 (15) 17 (18) 
Active malignancy, n (%)* 46 (14) 103 (40) — 
Diabetes, n (%) 17 (5.1) 12 (4.6) 6 (6.3) 
Active smoker, n (%) 110 (33) 78 (30) 30 (32) 
Use of blood pressure–lowering medication, n (%) 107 (32) 91 (35) 34 (36) 
Use of antiplatelet therapy, n (%) 50 (15) 37 (14) 17 (18) 
Use of lipid-lowering medication, n (%) 57 (17) 42 (16) 18 (19) 
No. of patient-years in follow-up 1284 817 349 
Control patients (n = 334)Patients with provoked PE (n = 259)Patients with unprovoked PE (n = 95)
Sex (female), %* 211 (63) 137 (53) 49 (55) 
Age, y (mean ± SD)* 48 ± 17 52 ± 18 55 ± 17 
History of arterial cardiovascular events, n (%) 40 (12) 38 (15) 17 (18) 
Active malignancy, n (%)* 46 (14) 103 (40) — 
Diabetes, n (%) 17 (5.1) 12 (4.6) 6 (6.3) 
Active smoker, n (%) 110 (33) 78 (30) 30 (32) 
Use of blood pressure–lowering medication, n (%) 107 (32) 91 (35) 34 (36) 
Use of antiplatelet therapy, n (%) 50 (15) 37 (14) 17 (18) 
Use of lipid-lowering medication, n (%) 57 (17) 42 (16) 18 (19) 
No. of patient-years in follow-up 1284 817 349 

PE indicates pulmonary embolism; and —, not applicable.

*

Significantly different.

At time of presentation with clinically suspected acute PE.

After hospital discharge.

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