Monoclonal antibodies
Designation* . | Isotype . | Specificity . |
---|---|---|
3E7/H17†‡ | Murine IgG1 | C3b, iC3b |
1H8‡ | Murine IgG2a | C3b, iC3b, C3dg |
7C12‡ | Murine IgG1 | C3b, iC3b |
5G9§ | Murine IgG2a | C3b, iC3b |
8B3‖ | Murine IgG1 | Tumor necrosis factor |
CD59 | Murine IgG2a | CD59 |
Designation* . | Isotype . | Specificity . |
---|---|---|
3E7/H17†‡ | Murine IgG1 | C3b, iC3b |
1H8‡ | Murine IgG2a | C3b, iC3b, C3dg |
7C12‡ | Murine IgG1 | C3b, iC3b |
5G9§ | Murine IgG2a | C3b, iC3b |
8B3‖ | Murine IgG1 | Tumor necrosis factor |
CD59 | Murine IgG2a | CD59 |
mAb indicates monoclonal antibody.
When mAbs are fluorescently labeled, the fluorochrome is included in the name of the mAb (eg, Al647 mAb H17 is mAb H17 labeled with Al647).
Blocks the alternative pathway of complement. H17 is a chimeric-deimmunized version of 3E7.
Nonoverlapping epitopes.
Blocks the classical pathway of complement.
Used as an isotype matched control.