Parameters of thrombin generation in mouse PRP
| . | PN-1+/+ . | PN-1−/− . | PAI-1+/+ . | PAI-1−/− . |
|---|---|---|---|---|
| Lag time, min | 4.6 ± 0.5 | 3.2 ± 0.5* | 4.1 ± 0.4 | 3.9 ± 0.6 |
| Time to peak, min | 9.4 ± 0.4 | 6.9 ± 0.7* | 8.4 ± 0.3 | 8.7 ± 1.2 |
| Peak height, nM | 36.8 ± 4.3 | 51.5 ± 4.7* | 49.2 ± 2.2 | 40.4 ± 2.1* |
| ETP, nM thrombin × min | 499.8 ± 44 | 527.4 ± 17 | 541 ± 81 | 470 ± 10.6 |
| . | PN-1+/+ . | PN-1−/− . | PAI-1+/+ . | PAI-1−/− . |
|---|---|---|---|---|
| Lag time, min | 4.6 ± 0.5 | 3.2 ± 0.5* | 4.1 ± 0.4 | 3.9 ± 0.6 |
| Time to peak, min | 9.4 ± 0.4 | 6.9 ± 0.7* | 8.4 ± 0.3 | 8.7 ± 1.2 |
| Peak height, nM | 36.8 ± 4.3 | 51.5 ± 4.7* | 49.2 ± 2.2 | 40.4 ± 2.1* |
| ETP, nM thrombin × min | 499.8 ± 44 | 527.4 ± 17 | 541 ± 81 | 470 ± 10.6 |
Values are the mean ± SD of 3 experiments performed in triplicate.
P < .05.