Parameters of thrombin generation in human PRP
| . | PRP alone . | PRP + anti–PN-1 . | PRP + anti–PAI-1 . | PRP + irrelevant IgG . |
|---|---|---|---|---|
| Lag time, min | 5.3 ± 0.3 | 5.4 ± 0.5 | 5.5 ± 0.2 | 5.2 ± 0.5 |
| Time to peak, min | 15.3 ± 1.8 | 11.3 ± 1.5* | 12.3 ± 1.6 | 13.9 ± 3.2 |
| Peak height, nM | 124.4 ± 32.6 | 187.9 ± 11.5* | 132.2 ± 33 | 124.5 ± 17.6 |
| ETP, nM thrombin × min | 1640.1 ± 244 | 1540.3 ± 233 | 1701.2 ± 415 | 1509.5 ± 81 |
| . | PRP alone . | PRP + anti–PN-1 . | PRP + anti–PAI-1 . | PRP + irrelevant IgG . |
|---|---|---|---|---|
| Lag time, min | 5.3 ± 0.3 | 5.4 ± 0.5 | 5.5 ± 0.2 | 5.2 ± 0.5 |
| Time to peak, min | 15.3 ± 1.8 | 11.3 ± 1.5* | 12.3 ± 1.6 | 13.9 ± 3.2 |
| Peak height, nM | 124.4 ± 32.6 | 187.9 ± 11.5* | 132.2 ± 33 | 124.5 ± 17.6 |
| ETP, nM thrombin × min | 1640.1 ± 244 | 1540.3 ± 233 | 1701.2 ± 415 | 1509.5 ± 81 |
Values are the mean ± SD of 5 experiments performed in triplicate.
P < .05.