Patient, donor, and transplantation characteristics
| Variable . | n . |
|---|---|
| Donor sex, male/female | 438/183 |
| Donor median age, y (range) | 35 (19-56) |
| Donor CMV status, positive/negative/missing | 327/284/10 |
| Patient sex, male/female | 352/269 |
| Patient median age, y (range) | 41 (18-66) |
| Patient CMV status, positive/negative/missing | 336/77/208 |
| HSCT year | |
| 1999-2000 | 13/35 |
| 2001-2002 | 47/84 |
| 2003-2004 | 113/111 |
| 2005-2006 | 141/77 |
| ATG use, yes/no/missing | 422/153/46 |
| Diagnosis | |
| Acute lymphoblastic leukemia | 119 |
| Acute myeloid leukemia | 193 |
| Chronic lymphocytic leukemia | 11 |
| Chronic myeloid leukemia | 76 |
| Hodgkin lymphoma | 24 |
| Myelodysplastic syndrome | 63 |
| Multiple myeloma | 41 |
| Myeloproliferative syndrome | 21 |
| Non-Hodgkin lymphoma | 60 |
| Secondary acute leukemia | 13 |
| Disease group, CML-CP1/AL-CR1/ADV | 31/127/463 |
| Stem cell source, PBSC/BM/missing | 249/368/4 |
| Conditioning, MA/RIC/missing | 427/161/33 |
| TBI use, yes/no/missing | 359/250/12 |
| HLA matching | |
| 12 of 12 allele-matched | 41 |
| 10 of 10 allele-matched, DPB1 mismatched | 201 |
| 9 of 10 allele-matched, DPB1 mismatched | 199 |
| Less than or equal to 8 of 10 allele-matched, DPB1 mismatched | 137 |
| DPB1-matched, mismatched at other loci | 43 |
| DRB3/4/5-matched/DRB3/4/5 typed | 550/616 |
| DQA1-matched/DQA1 typed | 516/537 |
| DPA1-matched/DPA1 typed | 146/277 |
| Permissive/nonpermissive HLA-DPB1 disparity | |
| Mismatched permissive TCE3/TCE4 | 287/158 |
| Mismatched nonpermissive (GvH) TCE3/TCE4 | 145/219 |
| Mismatched nonpermissive (HvG) TCE3/TCE4 | 105/160 |
| Variable . | n . |
|---|---|
| Donor sex, male/female | 438/183 |
| Donor median age, y (range) | 35 (19-56) |
| Donor CMV status, positive/negative/missing | 327/284/10 |
| Patient sex, male/female | 352/269 |
| Patient median age, y (range) | 41 (18-66) |
| Patient CMV status, positive/negative/missing | 336/77/208 |
| HSCT year | |
| 1999-2000 | 13/35 |
| 2001-2002 | 47/84 |
| 2003-2004 | 113/111 |
| 2005-2006 | 141/77 |
| ATG use, yes/no/missing | 422/153/46 |
| Diagnosis | |
| Acute lymphoblastic leukemia | 119 |
| Acute myeloid leukemia | 193 |
| Chronic lymphocytic leukemia | 11 |
| Chronic myeloid leukemia | 76 |
| Hodgkin lymphoma | 24 |
| Myelodysplastic syndrome | 63 |
| Multiple myeloma | 41 |
| Myeloproliferative syndrome | 21 |
| Non-Hodgkin lymphoma | 60 |
| Secondary acute leukemia | 13 |
| Disease group, CML-CP1/AL-CR1/ADV | 31/127/463 |
| Stem cell source, PBSC/BM/missing | 249/368/4 |
| Conditioning, MA/RIC/missing | 427/161/33 |
| TBI use, yes/no/missing | 359/250/12 |
| HLA matching | |
| 12 of 12 allele-matched | 41 |
| 10 of 10 allele-matched, DPB1 mismatched | 201 |
| 9 of 10 allele-matched, DPB1 mismatched | 199 |
| Less than or equal to 8 of 10 allele-matched, DPB1 mismatched | 137 |
| DPB1-matched, mismatched at other loci | 43 |
| DRB3/4/5-matched/DRB3/4/5 typed | 550/616 |
| DQA1-matched/DQA1 typed | 516/537 |
| DPA1-matched/DPA1 typed | 146/277 |
| Permissive/nonpermissive HLA-DPB1 disparity | |
| Mismatched permissive TCE3/TCE4 | 287/158 |
| Mismatched nonpermissive (GvH) TCE3/TCE4 | 145/219 |
| Mismatched nonpermissive (HvG) TCE3/TCE4 | 105/160 |