Table 3

Overview of completed/ongoing phase 3 clinical trials involving dabigatran

ComparatorNo. (approximate) of patientsResults expected/publishedAcronym
AF VKA 18 000 200911  RELY 
VTE primary prophylaxis, orthopedic LMWH 7 500 2007-20098-10  RE-NOVATE, RE-MOBILIZE, RE-MODEL 
VTE acute treatment VKA (patients will have LMWH therapy during the first week of therapy with dabigatran or VKA) 2 600 2011, 2012 RECOVER 
VTE secondary prevention Placebo (before randomization, all patients have received 6-18 months of anticoagulation) 4 500 2011 REMEDY, RECOVER II 
ComparatorNo. (approximate) of patientsResults expected/publishedAcronym
AF VKA 18 000 200911  RELY 
VTE primary prophylaxis, orthopedic LMWH 7 500 2007-20098-10  RE-NOVATE, RE-MOBILIZE, RE-MODEL 
VTE acute treatment VKA (patients will have LMWH therapy during the first week of therapy with dabigatran or VKA) 2 600 2011, 2012 RECOVER 
VTE secondary prevention Placebo (before randomization, all patients have received 6-18 months of anticoagulation) 4 500 2011 REMEDY, RECOVER II 

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