Table 2

Three- or two-cohort classification using 11 biomarkers

Phenotypic classGenotypic class (microarray)
NormalRTETTotal
Three-way classification     
    Normal 42 (87.5) 5 (10.4) 1 (2.1) 48 
    RT 23 (100) 23 
    ET 1 (4.2) 6 (25.0) 17 (70.8) 24 
    Classification by group aggregate    82/95 (86.3%) 
Two-way classification     
    RT — 23 (100) 0 (0) 23 
    ET — 3 (12.5) 21 (87.5) 24 
    Classification by group aggregate    44/47 (93.6%) 
Phenotypic classGenotypic class (microarray)
NormalRTETTotal
Three-way classification     
    Normal 42 (87.5) 5 (10.4) 1 (2.1) 48 
    RT 23 (100) 23 
    ET 1 (4.2) 6 (25.0) 17 (70.8) 24 
    Classification by group aggregate    82/95 (86.3%) 
Two-way classification     
    RT — 23 (100) 0 (0) 23 
    ET — 3 (12.5) 21 (87.5) 24 
    Classification by group aggregate    44/47 (93.6%) 

Classification was completed using nonparametric LDA with a leave-one-out cross-validation (numbers in parentheses are percentage by group). A subject is classified to the group corresponding to his/her highest posterior classification probability (both 3-way and 2-way classifications are delineated).

— indicates not applicable.

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