Table 4

Univariate and multivariate statistical analysis of the prognostic factors for actually receiving a transplant, according to the intention to treat and for overall survival and progression-free survival in 50 eligible patients

Prognostic factorsPossibility to receive a transplant
Overall survival
Progression-free survival
UnivariateMultivariateUnivariateMultivariateUnivariateMultivariate
Stage IV 0.004 0.025 0.006 0.196 0.022 0.49 
    OR (95% CI)  5.72 (1.24-26.38)  2.14 (0.67-6.84)  1.48 (0.48-4.58) 
Marrow involvement NS NS 0.002 <0.001 0.024 0.009 
    OR (95% CI)    5.28 (2.0-13.93)  3.49 (1.32-8.96) 
Systemic symptoms NS NS 0.011 0.964 0.082 0.755 
    OR (95% CI)    0.97 (0.35-2.68)  0.85 (0.32-2.24) 
Performance status 2 NS NS <0.001 0.001 0.018 0.067 
    OR (95% CI)    3.84 (1.66-8.86)  2.23 (0.94-5.29) 
CD4+ count < 100/μL 0.006 0.008 0.002 <0.001 0.001 <0.001 
    OR (95% CI)  25.44 (2.27-284.7)  6.71 (2.5-18.01)  6.14 (2.36-15.99) 
Prognostic factorsPossibility to receive a transplant
Overall survival
Progression-free survival
UnivariateMultivariateUnivariateMultivariateUnivariateMultivariate
Stage IV 0.004 0.025 0.006 0.196 0.022 0.49 
    OR (95% CI)  5.72 (1.24-26.38)  2.14 (0.67-6.84)  1.48 (0.48-4.58) 
Marrow involvement NS NS 0.002 <0.001 0.024 0.009 
    OR (95% CI)    5.28 (2.0-13.93)  3.49 (1.32-8.96) 
Systemic symptoms NS NS 0.011 0.964 0.082 0.755 
    OR (95% CI)    0.97 (0.35-2.68)  0.85 (0.32-2.24) 
Performance status 2 NS NS <0.001 0.001 0.018 0.067 
    OR (95% CI)    3.84 (1.66-8.86)  2.23 (0.94-5.29) 
CD4+ count < 100/μL 0.006 0.008 0.002 <0.001 0.001 <0.001 
    OR (95% CI)  25.44 (2.27-284.7)  6.71 (2.5-18.01)  6.14 (2.36-15.99) 

Only those parameters that achieved statistical or borderline significance on at least one endpoint are listed.

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