Univariate and multivariate statistical analysis of the prognostic factors for actually receiving a transplant, according to the intention to treat and for overall survival and progression-free survival in 50 eligible patients
Prognostic factors . | Possibility to receive a transplant . | Overall survival . | Progression-free survival . | |||
---|---|---|---|---|---|---|
Univariate . | Multivariate . | Univariate . | Multivariate . | Univariate . | Multivariate . | |
Stage IV | 0.004 | 0.025 | 0.006 | 0.196 | 0.022 | 0.49 |
OR (95% CI) | 5.72 (1.24-26.38) | 2.14 (0.67-6.84) | 1.48 (0.48-4.58) | |||
Marrow involvement | NS | NS | 0.002 | <0.001 | 0.024 | 0.009 |
OR (95% CI) | 5.28 (2.0-13.93) | 3.49 (1.32-8.96) | ||||
Systemic symptoms | NS | NS | 0.011 | 0.964 | 0.082 | 0.755 |
OR (95% CI) | 0.97 (0.35-2.68) | 0.85 (0.32-2.24) | ||||
Performance status 2 | NS | NS | <0.001 | 0.001 | 0.018 | 0.067 |
OR (95% CI) | 3.84 (1.66-8.86) | 2.23 (0.94-5.29) | ||||
CD4+ count < 100/μL | 0.006 | 0.008 | 0.002 | <0.001 | 0.001 | <0.001 |
OR (95% CI) | 25.44 (2.27-284.7) | 6.71 (2.5-18.01) | 6.14 (2.36-15.99) |
Prognostic factors . | Possibility to receive a transplant . | Overall survival . | Progression-free survival . | |||
---|---|---|---|---|---|---|
Univariate . | Multivariate . | Univariate . | Multivariate . | Univariate . | Multivariate . | |
Stage IV | 0.004 | 0.025 | 0.006 | 0.196 | 0.022 | 0.49 |
OR (95% CI) | 5.72 (1.24-26.38) | 2.14 (0.67-6.84) | 1.48 (0.48-4.58) | |||
Marrow involvement | NS | NS | 0.002 | <0.001 | 0.024 | 0.009 |
OR (95% CI) | 5.28 (2.0-13.93) | 3.49 (1.32-8.96) | ||||
Systemic symptoms | NS | NS | 0.011 | 0.964 | 0.082 | 0.755 |
OR (95% CI) | 0.97 (0.35-2.68) | 0.85 (0.32-2.24) | ||||
Performance status 2 | NS | NS | <0.001 | 0.001 | 0.018 | 0.067 |
OR (95% CI) | 3.84 (1.66-8.86) | 2.23 (0.94-5.29) | ||||
CD4+ count < 100/μL | 0.006 | 0.008 | 0.002 | <0.001 | 0.001 | <0.001 |
OR (95% CI) | 25.44 (2.27-284.7) | 6.71 (2.5-18.01) | 6.14 (2.36-15.99) |
Only those parameters that achieved statistical or borderline significance on at least one endpoint are listed.