Engraftment and transplantation-related toxicities (n = 53*)
. | Value . |
---|---|
Median duration of neutropenia (ANC < 0.5 × 109/L), d (range) | 7 (4-15) |
Median duration of thrombocytopenia, d (range) | |
Less than 20 × 109/L | 3 (0-11) |
Less than 50 × 109/L | 9 (3-31) |
Median no. of platelet transfusions (range) | 2 (0-7) |
Median no. of packed red blood cell transfusions (range) | 1 (0-4) |
Median duration of fever, d (range) | 3 (0-10) |
Mucositis | |
All grades, n (%) | 37 (70) |
Grade 3 or 4, n (%) | 25 (47) |
Median duration of mucositis, d (range) | 9 (2-13) |
GI tract/diarrhea grade 1 or 2, n (%) | 38 (72) |
Dermatologic/allergic reactions grade 1 or 2, n (%) | 18 (34) |
Peripheral neuropathy (de novo), n (%) | 3 (6) |
Headache, n (%) | 15 (28) |
Toxic death, n | 0 |
. | Value . |
---|---|
Median duration of neutropenia (ANC < 0.5 × 109/L), d (range) | 7 (4-15) |
Median duration of thrombocytopenia, d (range) | |
Less than 20 × 109/L | 3 (0-11) |
Less than 50 × 109/L | 9 (3-31) |
Median no. of platelet transfusions (range) | 2 (0-7) |
Median no. of packed red blood cell transfusions (range) | 1 (0-4) |
Median duration of fever, d (range) | 3 (0-10) |
Mucositis | |
All grades, n (%) | 37 (70) |
Grade 3 or 4, n (%) | 25 (47) |
Median duration of mucositis, d (range) | 9 (2-13) |
GI tract/diarrhea grade 1 or 2, n (%) | 38 (72) |
Dermatologic/allergic reactions grade 1 or 2, n (%) | 18 (34) |
Peripheral neuropathy (de novo), n (%) | 3 (6) |
Headache, n (%) | 15 (28) |
Toxic death, n | 0 |
ANC indicates absolute neutrophil count; and GI, gastrointestinal.
One patient did not receive the planned autologous stem cell transplantation because of pulmonary aspergillosis.