ATRA induces expression of CCLs and CCRs in NB4 cells
. | Gene expression intensity before ATRA, AU . | Maximum gene expression intensity after ATRA, AU . | Fold change . |
---|---|---|---|
CCL2 | 71 | 10 285 | 151 |
CCL22 | 18 | 1822 | 104 |
CCL24 | 13 | 969 | 78 |
CCL4 | 14 | 896 | 61 |
CCL20 | 72 | 1441 | 21 |
CCL3 | 181 | 3576 | 20 |
CCL1 | 42 | 754 | 19 |
CCL7 | 19 | 108 | 6 |
CCR1 | 48 | 1331 | 28 |
CCR2 | 41 | 851 | 21 |
CCR3 | 25 | 489 | 19 |
. | Gene expression intensity before ATRA, AU . | Maximum gene expression intensity after ATRA, AU . | Fold change . |
---|---|---|---|
CCL2 | 71 | 10 285 | 151 |
CCL22 | 18 | 1822 | 104 |
CCL24 | 13 | 969 | 78 |
CCL4 | 14 | 896 | 61 |
CCL20 | 72 | 1441 | 21 |
CCL3 | 181 | 3576 | 20 |
CCL1 | 42 | 754 | 19 |
CCL7 | 19 | 108 | 6 |
CCR1 | 48 | 1331 | 28 |
CCR2 | 41 | 851 | 21 |
CCR3 | 25 | 489 | 19 |
mRNA expression of CCLs and CCRs was determined in total RNA from NB4 cells cultured with ATRA (10−6 M) for 0, 4, 8, 24, 48, 72, and 96 hours using the GeneChip Human Exon 1.0 ST Array. The table represents chemokines and receptors with at least 5-fold up-regulation of the gene expression intensity in arbitrary units (AUs) after ATRA treatment.