Prevalence of MGUS in first-degree relatives of MGUS and myeloma (MM) probands compared with Olmsted County, MN residents
| Age, y . | All relatives . | Relatives of MGUS proband . | Relatives of MM proband . | Olmsted County . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total No. . | No. with MGUS . | Prevalence (95% CI) . | Total No. . | No. with MGUS . | Prevalence (95% CI) . | Total No. . | No. with MGUS . | Prevalence (95% CI) . | TotalNo. . | No. with MGUS . | Prevalence (95% CI) . | |
| 40-49 | 258 | 2 | 0.8 (0.1-2.8) | 57 | 0 | 0 (0.0-6.2) | 201 | 2 | 1.0 (0.1-3.5) | |||
| 50-59 | 233 | 11 | 4.7 (2.4-8.3) | 76 | 5 | 6.6 (2.2-14.7) | 157 | 6 | 3.8 (1.4-8.1) | 8373 | 141 | 1.7 (1.4-2.0) |
| 60-69 | 190 | 14 | 7.4 (4.1-12.1) | 47 | 3 | 6.4 (1.3-17.5) | 143 | 11 | 7.7 (3.9-13.3) | 6019 | 178 | 3.0 (2.5-3.4) |
| 70-79 | 130 | 15 | 11.5 (6.6-18.3) | 39 | 8 | 20.5 (9.3-36.5) | 91 | 7 | 7.7 (3.1-15.2) | 4508 | 205 | 4.6 (4.0-5.2) |
| 80+ | 100 | 13 | 13.0 (7.1-21.2) | 28 | 6 | 21.4 (8.3-41.0) | 72 | 7 | 9.7 (4.0-19.0) | 2563 | 170 | 6.6 (5.7-7.7) |
| Total, adjusted* | 911 | 55 | 5.4 (3.9-6.8) | 247 | 22 | 7.4 (4.2-10.7) | 664 | 33 | 4.5 (2.9-6.1) | 21463 | 694 | 3.2 (3.0-3.5) |
| Total, adjusted† | 911 | 83 | 8.1 (6.3-9.8) | 247 | 30 | 10.9 (6.8-15.0) | 664 | 53 | 7.0 (5.1-9.0) | |||
| Age, y . | All relatives . | Relatives of MGUS proband . | Relatives of MM proband . | Olmsted County . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total No. . | No. with MGUS . | Prevalence (95% CI) . | Total No. . | No. with MGUS . | Prevalence (95% CI) . | Total No. . | No. with MGUS . | Prevalence (95% CI) . | TotalNo. . | No. with MGUS . | Prevalence (95% CI) . | |
| 40-49 | 258 | 2 | 0.8 (0.1-2.8) | 57 | 0 | 0 (0.0-6.2) | 201 | 2 | 1.0 (0.1-3.5) | |||
| 50-59 | 233 | 11 | 4.7 (2.4-8.3) | 76 | 5 | 6.6 (2.2-14.7) | 157 | 6 | 3.8 (1.4-8.1) | 8373 | 141 | 1.7 (1.4-2.0) |
| 60-69 | 190 | 14 | 7.4 (4.1-12.1) | 47 | 3 | 6.4 (1.3-17.5) | 143 | 11 | 7.7 (3.9-13.3) | 6019 | 178 | 3.0 (2.5-3.4) |
| 70-79 | 130 | 15 | 11.5 (6.6-18.3) | 39 | 8 | 20.5 (9.3-36.5) | 91 | 7 | 7.7 (3.1-15.2) | 4508 | 205 | 4.6 (4.0-5.2) |
| 80+ | 100 | 13 | 13.0 (7.1-21.2) | 28 | 6 | 21.4 (8.3-41.0) | 72 | 7 | 9.7 (4.0-19.0) | 2563 | 170 | 6.6 (5.7-7.7) |
| Total, adjusted* | 911 | 55 | 5.4 (3.9-6.8) | 247 | 22 | 7.4 (4.2-10.7) | 664 | 33 | 4.5 (2.9-6.1) | 21463 | 694 | 3.2 (3.0-3.5) |
| Total, adjusted† | 911 | 83 | 8.1 (6.3-9.8) | 247 | 30 | 10.9 (6.8-15.0) | 664 | 53 | 7.0 (5.1-9.0) | |||