Table 3 Patients' heavy and light Ig... | American Society of Hematology

Table 3

Patients' heavy and light Ig gene pattern at the time of the study

Case	IgVH						IgVL
	VH	Mutation, %	D	J_H	Motif	HCDR3	VL	Mutation, %	J_L	Motif	LCDR3
	VH	Mutation, %	D	J_H	Motif	AA sequence	VL	Mutation, %	J_L	Motif	AA sequence
1	3-15	10.7	2-2	3b	GYSSTFDGAFDI	12	V_λ1-47	0.8	λ7	AAWDDSLSGR	10
2							V_κ3-15	1.9	κ1	QQPNNWPPTS	10
3	3-30	10.2	3-10	4b	GWFEKVPQEYFDS	13	V_κ2-30	3.1	κ2	MQGTHWIHTF	10
4	3-30	2.7	3-9	4b	TLGDEYDILTGYSKGYFDS	19	V_κ4-1	2.0	κ4	QQYYSTPLTF	10
5	3-33	7.4	5-24	4b	EKLRGDGYNQALDY	14	V_κ4-1	3.5	κ3	QQYYSPPYFT	10
6	3-07	7.7	5-24	5b	DLWADRGGPPSTRFDP	16	V_λ2-11	3.8	λ2	CSYAGSPTF	9
7	3-72	4.6	3-10	5b	VLDGGIHWFDP	11	V_κ4-1	8.3	κ2	QQYYSPPYTF	10
8	4-34	7.2	3-10	5b	ASVPGGSGSGPNCLDP	16	V_λ1-51	4.2	λ3	GTWDSSLSGRVF	12

Case	IgVH						IgVL
	VH	Mutation, %	D	J_H	Motif	HCDR3	VL	Mutation, %	J_L	Motif	LCDR3
	VH	Mutation, %	D	J_H	Motif	AA sequence	VL	Mutation, %	J_L	Motif	AA sequence
1	3-15	10.7	2-2	3b	GYSSTFDGAFDI	12	V_λ1-47	0.8	λ7	AAWDDSLSGR	10
2							V_κ3-15	1.9	κ1	QQPNNWPPTS	10
3	3-30	10.2	3-10	4b	GWFEKVPQEYFDS	13	V_κ2-30	3.1	κ2	MQGTHWIHTF	10
4	3-30	2.7	3-9	4b	TLGDEYDILTGYSKGYFDS	19	V_κ4-1	2.0	κ4	QQYYSTPLTF	10
5	3-33	7.4	5-24	4b	EKLRGDGYNQALDY	14	V_κ4-1	3.5	κ3	QQYYSPPYFT	10
6	3-07	7.7	5-24	5b	DLWADRGGPPSTRFDP	16	V_λ2-11	3.8	λ2	CSYAGSPTF	9
7	3-72	4.6	3-10	5b	VLDGGIHWFDP	11	V_κ4-1	8.3	κ2	QQYYSPPYTF	10
8	4-34	7.2	3-10	5b	ASVPGGSGSGPNCLDP	16	V_λ1-51	4.2	λ3	GTWDSSLSGRVF	12