Table 1

Genetic tests to be performed in myeloma patients at diagnosis

Essential tests for all patientsDesirable testsInvestigational tests for trials
  • Plasma cell–specific FISH analysis

    • t(4;14) (p16;q32)

    • t(14;16) (q32;q23)

    • 17p13

 
  • Cytogenetics

  • Plasma cell–specific FISH analysis

    • Hyperdiploidy

    • t(11;14)(q13;q32)

    • 1q amplifications

    • 1 p deletions

    • Loss of 12p

    • Gains of Cr5

 
  • Gene expression profiling

  • aCGH/SNP arrays

 
Essential tests for all patientsDesirable testsInvestigational tests for trials
  • Plasma cell–specific FISH analysis

    • t(4;14) (p16;q32)

    • t(14;16) (q32;q23)

    • 17p13

 
  • Cytogenetics

  • Plasma cell–specific FISH analysis

    • Hyperdiploidy

    • t(11;14)(q13;q32)

    • 1q amplifications

    • 1 p deletions

    • Loss of 12p

    • Gains of Cr5

 
  • Gene expression profiling

  • aCGH/SNP arrays

 

FISH indicates fluorescent in situ hybridizaton; and aCGH/SNP, array comparative genomic hybridization/single nucleotide polymorphisms.

Close Modal

or Create an Account

Close Modal
Close Modal