Table 1

Hematologic parameters of GbG mice that underwent transplantation after myeloablative conditioning

Mouse typeNo.WBC, 103/μLRBC, 106/μLHb, g/dLMCV, fLMCH, pgRDW, %Plt, 103/μLReticulocytes, %
BERK 56.8 ± 5.4 5.3 ± 0.4 5.8 ± 0.5 48.2 ± 1.05 10.7 ± 0.5 35.3 ± 1.6 733 ± 80 60.8 ± 5.0 
GbG pri 10.6 ± 3.1 9.4 ± 0.8 10.0 ± 0.8 40.7 ± 1.3 10.4 ± 0.6 27.6 ± 1.1 733 ± 82 15.8 ± 3.2 
Mock pri 10 29.7 ± 1.4 5.8 ± 0.4 7.6 ± 0.7 48.5 ± 1.8 10.7 ± 0.2 32.0 ± 0.9 921 ± 50 40.0 ± 3.0 
P*  .001 .007 .03 .001 .9 .009 .06 .006 
GbG sec 6.8 ± 1.4 8.9 ± 0.4 10.1 ± 0.5 40.5 ± 1.6 11.4 ± 0.5 28.3 ± 1.4 658 ± 33 13.8 ± 2.9 
Mock sec 31.7 5.2 6.4 47.6 12.2 32.1 923 49 
Mouse typeNo.WBC, 103/μLRBC, 106/μLHb, g/dLMCV, fLMCH, pgRDW, %Plt, 103/μLReticulocytes, %
BERK 56.8 ± 5.4 5.3 ± 0.4 5.8 ± 0.5 48.2 ± 1.05 10.7 ± 0.5 35.3 ± 1.6 733 ± 80 60.8 ± 5.0 
GbG pri 10.6 ± 3.1 9.4 ± 0.8 10.0 ± 0.8 40.7 ± 1.3 10.4 ± 0.6 27.6 ± 1.1 733 ± 82 15.8 ± 3.2 
Mock pri 10 29.7 ± 1.4 5.8 ± 0.4 7.6 ± 0.7 48.5 ± 1.8 10.7 ± 0.2 32.0 ± 0.9 921 ± 50 40.0 ± 3.0 
P*  .001 .007 .03 .001 .9 .009 .06 .006 
GbG sec 6.8 ± 1.4 8.9 ± 0.4 10.1 ± 0.5 40.5 ± 1.6 11.4 ± 0.5 28.3 ± 1.4 658 ± 33 13.8 ± 2.9 
Mock sec 31.7 5.2 6.4 47.6 12.2 32.1 923 49 

Hb indicates hemoglobin; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; RDW, red cell distribution width; Plt, platelets; pri, primary mice; and sec, secondary mice.

*

P values represent comparison of primary mock mice with the GbG group. Statistical comparisons of secondary mice were not made as only one secondary mock mouse was alive at the time of analysis.

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