Characteristics of the cases according to the presence or absence of a STAT6 mutation detected in exons 12-14
| . | STAT6 mutation (n = 20) . | No STAT6 mutation (n = 35) . | P* . |
|---|---|---|---|
| Median age at diagnosis, y (range) | 37.5 (22-59) | 32 (17-73) | .43 |
| Females/males | 13/7 | 15/20 | .16 |
| Ann Arbor stage at diagnosis | .71 | ||
| I-II | 11 | 16 | |
| III-IV | 3 | 7 | |
| Unknown | 6 | 12 | |
| P-STAT6 staining | .13 | ||
| Positive | 14 | 17 | |
| Negative | 0 | 4 | |
| Not evaluable | 6 | 14 | |
| SOCS1 gene alteration | .14 | ||
| Present | 15 | 19 | |
| Absent | 4 | 14 | |
| Not determined | 1 | 2 | |
| JAK2 gene amplification | .76 | ||
| Present | 7 | 15 | |
| Absent | 10 | 15 | |
| Not determined | 3 | 5 |
| . | STAT6 mutation (n = 20) . | No STAT6 mutation (n = 35) . | P* . |
|---|---|---|---|
| Median age at diagnosis, y (range) | 37.5 (22-59) | 32 (17-73) | .43 |
| Females/males | 13/7 | 15/20 | .16 |
| Ann Arbor stage at diagnosis | .71 | ||
| I-II | 11 | 16 | |
| III-IV | 3 | 7 | |
| Unknown | 6 | 12 | |
| P-STAT6 staining | .13 | ||
| Positive | 14 | 17 | |
| Negative | 0 | 4 | |
| Not evaluable | 6 | 14 | |
| SOCS1 gene alteration | .14 | ||
| Present | 15 | 19 | |
| Absent | 4 | 14 | |
| Not determined | 1 | 2 | |
| JAK2 gene amplification | .76 | ||
| Present | 7 | 15 | |
| Absent | 10 | 15 | |
| Not determined | 3 | 5 |
Age at diagnosis was compared with Wilcoxon rank test and the other characteristics were compared with Fisher exact test (using only informative cases).