Table 1

Relationship between IL-17 and clinical pathologic characteristics in ovarian cancer patients

VariableUnadjusted HR (95% CI)Adjusted HR (95% CI)
Age* 1.003 (0.98-1.03) NA 
Stage, II/III vs IV 1.84 (0.97-3.48) NA 
Grade, 0-2 vs 3 1.74 (0.80-3.78) NA 
Histology type, serous/mucinous/endometrial versus clear cells and undifferentiated 1.36 (0.69-2.69) NA 
Debulking, optimal versus suboptimal residual disease 0.17 (0.07-0.42) 0.189 (0.078-0.458) 
IL-17* 0.994 (0.992-0.997) 0.994 (0.991-0.997) 
VariableUnadjusted HR (95% CI)Adjusted HR (95% CI)
Age* 1.003 (0.98-1.03) NA 
Stage, II/III vs IV 1.84 (0.97-3.48) NA 
Grade, 0-2 vs 3 1.74 (0.80-3.78) NA 
Histology type, serous/mucinous/endometrial versus clear cells and undifferentiated 1.36 (0.69-2.69) NA 
Debulking, optimal versus suboptimal residual disease 0.17 (0.07-0.42) 0.189 (0.078-0.458) 
IL-17* 0.994 (0.992-0.997) 0.994 (0.991-0.997) 

NA indicates not applicable.

*

Age (in years) and IL-17 (in pg/mL) are continuous variables. Other variables are binary, as noted.

Adjusted HRs are based on a multivariable Cox proportional hazards model with debulking (binary: optimal vs suboptimal) and IL-17 (continuous) as covariates.

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