Table 4

MGUS among first-degree relatives of MGUS patients by sex of relative, type of relative, and age of probands at diagnosis

First-degree relatives of MGUS patients (n = 14621)First-degree relatives of controls (n = 58387)RR (95% CI)*
Sex of relative    
    Male 13 15 3.5 (1.5-8.5) 
    Female 16 2.2 (0.8-5.9) 
Type of first-degree relative    
    Parent 13 2.7 (1.2-6.3) 
    Sibling 4.9 (1.2-20) 
    Offspring 13 2.2 (0.9-5.6) 
Age at MGUS diagnosis for proband, y    
    Less than 65 15 18 3.2 (1.5-6.9) 
    65 or older 13 2.2 (0.9-5.5) 
First-degree relatives of MGUS patients (n = 14621)First-degree relatives of controls (n = 58387)RR (95% CI)*
Sex of relative    
    Male 13 15 3.5 (1.5-8.5) 
    Female 16 2.2 (0.8-5.9) 
Type of first-degree relative    
    Parent 13 2.7 (1.2-6.3) 
    Sibling 4.9 (1.2-20) 
    Offspring 13 2.2 (0.9-5.6) 
Age at MGUS diagnosis for proband, y    
    Less than 65 15 18 3.2 (1.5-6.9) 
    65 or older 13 2.2 (0.9-5.5) 
*

All estimates were adjusted for sex of first-degree relative.

Statistically significant (2-sided P value < .05).

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