Low-dose DPI treatment decreases MK polyploidy
| Ploidy . | Control . | 0.2 μM DPI . | P . |
|---|---|---|---|
| 2n | 5.73 ± 1.642 | 10.027 ± 0.954 | .017 |
| 4n | 4.00 ± 0.516 | 9.25 ± 1.107 | < .001 |
| 8n | 6.22 ± 0.855 | 17.613 ± 2.938 | .003 |
| 16n | 26.077 ± 1.727 | 31.267 ± 1.407 | .016 |
| 32n | 30.307 ± 2.432 | 6.773 ± 1.329 | < .001 |
| 64n | 12.373 ± 1.183 | 0.567 ± 0.306 | < .001 |
| Ploidy . | Control . | 0.2 μM DPI . | P . |
|---|---|---|---|
| 2n | 5.73 ± 1.642 | 10.027 ± 0.954 | .017 |
| 4n | 4.00 ± 0.516 | 9.25 ± 1.107 | < .001 |
| 8n | 6.22 ± 0.855 | 17.613 ± 2.938 | .003 |
| 16n | 26.077 ± 1.727 | 31.267 ± 1.407 | .016 |
| 32n | 30.307 ± 2.432 | 6.773 ± 1.329 | < .001 |
| 64n | 12.373 ± 1.183 | 0.567 ± 0.306 | < .001 |
Summary of ploidy status of 0.2 μM DPI-treated MKs expressed as a percentage ± SD of total MKs collected (summary of 3 independent experiments). Subgroups were compared with the t test.