QTLs identified with significant linkage to plasma VWF
| Locus . | Chromosome . | Position, Mbp . | Peak marker . | LOD . | P . |
|---|---|---|---|---|---|
| Mvwf5 | 6 | 114.1 | D6Mit329 | 11.65 | < .001 |
| Mvwf6 | 10 | 110.0 | D10Mit269 | 3.72 | .006 |
| Mvwf7 | 5 | 32.0 | D5Mit66 | 3.22 | .018 |
| Locus . | Chromosome . | Position, Mbp . | Peak marker . | LOD . | P . |
|---|---|---|---|---|---|
| Mvwf5 | 6 | 114.1 | D6Mit329 | 11.65 | < .001 |
| Mvwf6 | 10 | 110.0 | D10Mit269 | 3.72 | .006 |
| Mvwf7 | 5 | 32.0 | D5Mit66 | 3.22 | .018 |
Standard interval mapping was performed on natural log-transformed mean VWF levels from the B6 × WSB N2 population at 1-cM intervals by using the R/qtl package with adjustment for sex. P values represent the genomewide significance of LOD scores as determined by permutation testing.
QTL indicates quantitative trait locus; VWF, von Willebrand factor; and LOD, logarithm of odds.