Toxicity of treatment in the 19 evaluable patients
| . | No. of patients . |
|---|---|
| Hematologic toxicity (grade 3-4 WHO) | |
| Neutropenia/thrombocytopenia/anemia | 0/0/1 |
| Hematologic toxicity (grade 1-2 WHO) | |
| Neutropenia/thrombocytopenia/anemia | 1/1/1 |
| Extrahematologic toxicity (grade 3-4 WHO) | |
| Pneumonia | 1 |
| CNS viral infection (JCV) | 1 |
| Pleural effusion | 1 |
| Hydric retention/edema | 1 |
| Extrahematologic toxicity (grade 1-2 WHO) | |
| Gastroenteric/liver | 0/0 |
| Kidney/neurologic | 0/0 |
| Cardiovascular | 0 |
| Hydric retention/edema | 2 |
| Nausea or vomiting | 0 |
| Stop imatinib (causes) | |
| Yes/no | 8/11 |
| No response of cGVHD | 3 |
| Relapse of underlying disease requiring new treatment | 2 |
| Hydric retention* | 2 |
| CNS viral infection (JCV) | 1 |
| . | No. of patients . |
|---|---|
| Hematologic toxicity (grade 3-4 WHO) | |
| Neutropenia/thrombocytopenia/anemia | 0/0/1 |
| Hematologic toxicity (grade 1-2 WHO) | |
| Neutropenia/thrombocytopenia/anemia | 1/1/1 |
| Extrahematologic toxicity (grade 3-4 WHO) | |
| Pneumonia | 1 |
| CNS viral infection (JCV) | 1 |
| Pleural effusion | 1 |
| Hydric retention/edema | 1 |
| Extrahematologic toxicity (grade 1-2 WHO) | |
| Gastroenteric/liver | 0/0 |
| Kidney/neurologic | 0/0 |
| Cardiovascular | 0 |
| Hydric retention/edema | 2 |
| Nausea or vomiting | 0 |
| Stop imatinib (causes) | |
| Yes/no | 8/11 |
| No response of cGVHD | 3 |
| Relapse of underlying disease requiring new treatment | 2 |
| Hydric retention* | 2 |
| CNS viral infection (JCV) | 1 |
WHO indicates World Health Organization; CNS, central nervous system; JCV, John Cunningham virus; and cGVHD, chronic graft-versus-host disease.
Dead.