Table 2 Details of the main organ... | American Society of Hematology

Table 2

Details of the main organ involvement in the 19 patients with cGVHD

UPN	Skin fibrotic involvement		Zubrod PS	Lung involvement				Gut involvement		Bowel involvement GI score	Sicca syndrome	Biopsy	Schirmer test‡
	Skin fibrotic involvement			Basal respiratory functional tests			Basal LFS	Gut involvement
	BSA involved, %*	Total skin score†		FEV, %	FVC, %	DLCO, %	Basal LFS	Liver (bil > 2/ALP × 3 NR)	Bowel
1	100	49	1								No	Skin	6
1064	40	20	2	70	65	60	2		Diarrhea§	2	No	Skin	13
99991	100	44	2						Diarrhea§	2	Yes	Skin	2
99992	100	48	2	76	70	66	2		Diarrhea§	2	Yes	Skin	3
1467	Fasciitis: 90	51	3								Yes	Skin	5
1602	25	18	1	78	80	70	2				Yes	Skin	15
434	50	31	2	64	73	64	3				Yes	Skin	13
1346	Lung	NE	4	32	35	48	6				No	NE	15
122	100	46	2	44	50	60	5				Yes	Skin	4
143	25	21	1					N/474	Diarrhea§	3	Yes	Gut	15
1027	75‖	43	2								Yes	Skin	7
310AR	100¶	46	2	68	70	68	3	N/479			Yes	Gut	2
1992MP	100	47	2	65	72	70	3	2,3/N			Yes	Gut	3
401PP	100	51	3	60	70	74	3	N/386	Diarrhea§	3	Yes	Gut	5
8881047	80	42	2								Yes	Skin	5
1023015	75	41	1								Yes	Skin	5
1025779	30	24	2	74	78	72	2				Yes	Skin	15
1024411	90	43	3								Yes	Skin	5
9999450	30	23	3	70	68	68	1	N/567			No	Gut	10
Total	17/19*: 11 skin 75%-100%, 6 skin ≤ 50%	Range, 18-51	Range, 1-4	Range, 1-6	5/19	Range, 2-3					15/19	18/19

UPN	Skin fibrotic involvement		Zubrod PS	Lung involvement				Gut involvement		Bowel involvement GI score	Sicca syndrome	Biopsy	Schirmer test‡
	Skin fibrotic involvement			Basal respiratory functional tests			Basal LFS	Gut involvement
	BSA involved, %*	Total skin score†		FEV, %	FVC, %	DLCO, %	Basal LFS	Liver (bil > 2/ALP × 3 NR)	Bowel
1	100	49	1								No	Skin	6
1064	40	20	2	70	65	60	2		Diarrhea§	2	No	Skin	13
99991	100	44	2						Diarrhea§	2	Yes	Skin	2
99992	100	48	2	76	70	66	2		Diarrhea§	2	Yes	Skin	3
1467	Fasciitis: 90	51	3								Yes	Skin	5
1602	25	18	1	78	80	70	2				Yes	Skin	15
434	50	31	2	64	73	64	3				Yes	Skin	13
1346	Lung	NE	4	32	35	48	6				No	NE	15
122	100	46	2	44	50	60	5				Yes	Skin	4
143	25	21	1					N/474	Diarrhea§	3	Yes	Gut	15
1027	75‖	43	2								Yes	Skin	7
310AR	100¶	46	2	68	70	68	3	N/479			Yes	Gut	2
1992MP	100	47	2	65	72	70	3	2,3/N			Yes	Gut	3
401PP	100	51	3	60	70	74	3	N/386	Diarrhea§	3	Yes	Gut	5
8881047	80	42	2								Yes	Skin	5
1023015	75	41	1								Yes	Skin	5
1025779	30	24	2	74	78	72	2				Yes	Skin	15
1024411	90	43	3								Yes	Skin	5
9999450	30	23	3	70	68	68	1	N/567			No	Gut	10
Total	17/19*: 11 skin 75%-100%, 6 skin ≤ 50%	Range, 18-51	Range, 1-4	Range, 1-6	5/19	Range, 2-3					15/19	18/19

BSA, body surface area (generalized scleroderma was 75%-100% BSA); PS, performance status; NE, not evaluable; bil, bilirubin total (normal range, 0-1.5 mg/dL); ALP, alkaline phosphatase (normal range, 38-126 UI/L); FEV, forced expiratory volume; FVC, forced vital capacity; DLCO, carbon monoxide lung diffusion capacity; LFS-SCORE, Lung Function Score according to National Institutes of Health (NIH) consensus conference²¹; GI-SCORE, Gastrointestinal Score according to NIH consensus conference²¹; and N, normal.

†

According to the modified Rodnan score system.²²

‡

Millimeters of wetting of the paper after 5 minutes; the value is the mean of both eyes.

More than 1000 mL per day.

‖

Ulcer involvement: 25% skin.

Erythema: 80% skin.

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