Univariate analysis of risk factors (only with P ≤ .1) after reduced-intensity conditioning and allogeneic stem cell transplantation for myelofibrosis
| Variable . | 5-year overall survival . | P . | 3-year disease-free survival . | P . | NRM at 1 year . | P . | Relapse at 3 years . | P . |
|---|---|---|---|---|---|---|---|---|
| Lille score | .07 | .01 | .02 | |||||
| Low | 94 (82-100) | 80 (60-100) | — | 14 (0-32) | ||||
| Intermediate | 63 (46-80) | 61 (47-75) | — | 22 (9-35) | ||||
| High | 64 (47-81) | 41 (21-61) | — | 34 (16-52) | ||||
| HLA | .003 | .01 | .003 | |||||
| Matched | 74 (62-86) | 63 (52-74) | 12 (5-19) | — | ||||
| Mismatched | 38 (5-71) | 39 (16-62) | 38 (15-61) | — | ||||
| Age | .03 | |||||||
| Less than or equal to 55 y | 82 (71-93) | — | — | — | ||||
| More than 55 y | 48 (26-70) | — | — | — | ||||
| Splenectomy | .06 | .005 | ||||||
| Yes | — | 39 (12-66) | — | 51 (20-82) | ||||
| No | — | 61 (47-75) | — | 20 (10-30) |
| Variable . | 5-year overall survival . | P . | 3-year disease-free survival . | P . | NRM at 1 year . | P . | Relapse at 3 years . | P . |
|---|---|---|---|---|---|---|---|---|
| Lille score | .07 | .01 | .02 | |||||
| Low | 94 (82-100) | 80 (60-100) | — | 14 (0-32) | ||||
| Intermediate | 63 (46-80) | 61 (47-75) | — | 22 (9-35) | ||||
| High | 64 (47-81) | 41 (21-61) | — | 34 (16-52) | ||||
| HLA | .003 | .01 | .003 | |||||
| Matched | 74 (62-86) | 63 (52-74) | 12 (5-19) | — | ||||
| Mismatched | 38 (5-71) | 39 (16-62) | 38 (15-61) | — | ||||
| Age | .03 | |||||||
| Less than or equal to 55 y | 82 (71-93) | — | — | — | ||||
| More than 55 y | 48 (26-70) | — | — | — | ||||
| Splenectomy | .06 | .005 | ||||||
| Yes | — | 39 (12-66) | — | 51 (20-82) | ||||
| No | — | 61 (47-75) | — | 20 (10-30) |
Values are shown as percentages (95% CI).
— indicates not applicable.