Table 1

Steady-state parameters in children with and without cerebrovascular disease

Baseline parameterCerebrovascular disease
No cerebrovascular disease
OR (95% CI)
P
Mean ± SDnMean ± SDn
WBC, ×109/L 12.8 ± 4.1 59 11.5 ± 4.6 192 1.062 (1.00-1.13) .057 
Hb, g/dL 7.6 ± 0.88 59 8.4 ± 1.3 192 0.52 (0.36-0.71) <.001 
MCH, pg 28.9 ± 3.4 59 27.5 ± 3.8 192 1.12 (1.02-1.21) .011 
Reticulocyte, ×109/L 380 ± 140 58 329 ± 112 190 1.003 (1.001-1.006) .005 
AST, IU/L 62 ± 23 59 53 ± 16 192 1.03 (1.01-1.04) .003 
LDH, IU/L 659 ± 162 48 545 ± 158 185 1.004 (1.002-1.006) <.001 
HbF, % 8.0 ± 4.7 52 10.9 ± 7.7 176 0.93 (0.88-0.99) .012 
Baseline parameterCerebrovascular disease
No cerebrovascular disease
OR (95% CI)
P
Mean ± SDnMean ± SDn
WBC, ×109/L 12.8 ± 4.1 59 11.5 ± 4.6 192 1.062 (1.00-1.13) .057 
Hb, g/dL 7.6 ± 0.88 59 8.4 ± 1.3 192 0.52 (0.36-0.71) <.001 
MCH, pg 28.9 ± 3.4 59 27.5 ± 3.8 192 1.12 (1.02-1.21) .011 
Reticulocyte, ×109/L 380 ± 140 58 329 ± 112 190 1.003 (1.001-1.006) .005 
AST, IU/L 62 ± 23 59 53 ± 16 192 1.03 (1.01-1.04) .003 
LDH, IU/L 659 ± 162 48 545 ± 158 185 1.004 (1.002-1.006) <.001 
HbF, % 8.0 ± 4.7 52 10.9 ± 7.7 176 0.93 (0.88-0.99) .012 

Cerebrovascular disease is defined as the presence of either TAMMX >169 cm/s, clinical and radiologic evidence of an overt stroke, or both.

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